McLennan John D
Child psychiatrist at the Children's Hospital of Eastern Ontario in Ottawa, a scientist at the Children's Hospital of Eastern Ontario Research Institute, Research Chair in Child & Adolescent Psychiatry at the University of Ottawa, and Adjunct Associate Professor at the University of Calgary in Alberta.
Can Fam Physician. 2016 Dec;62(12):979-982.
To review research findings that consider whether attention deficit hyperactivity disorder (ADHD) is a discrete entity or whether it is more consistent with an extreme end-of-trait distribution in the population and to then grapple with the potential clinical implications.
Peer-reviewed publications in the past 5 years, drawing from diverse fields (taxonomy, epidemiology, genetics, neurobiology, and neuropsychology), were identified through searches in MEDLINE and PsycINFO.
Accumulating research findings are most consistent with a predominately dimensional rather than a qualitatively distinct existence for ADHD. This does not negate the clinical needs of those who have substantial ADHD symptom clusters, nor the risks that such symptoms entail. However, the lack of discontinuity in the distribution of such traits in the population creates great uncertainty as to what thresholds should prompt explicit intervention.
The implications of this pattern of findings might include the need to de-emphasize categorical conceptualizations of ADHD, produce evidence to better inform risk-benefit ratios of interventions along a spectrum of symptom and functional severity, and more coherently triage and arrange service delivery on the basis of symptom and functional severity rather than artificial diagnostic categorizations.
回顾关于注意力缺陷多动障碍(ADHD)是一个离散实体,还是更符合人群中特质分布极端情况的研究结果,进而探讨其潜在的临床意义。
通过检索MEDLINE和PsycINFO,从不同领域(分类学、流行病学、遗传学、神经生物学和神经心理学)筛选出过去5年经过同行评审的出版物。
越来越多的研究结果最符合ADHD主要是维度性的而非质性上截然不同的存在这一观点。这并不否定那些有大量ADHD症状群的人的临床需求,也不否定这些症状所带来的风险。然而,此类特质在人群中的分布缺乏间断性,这就导致对于何种阈值应促使进行明确干预存在很大的不确定性。
这一研究结果模式的影响可能包括需要淡化ADHD的分类概念,提供证据以更好地为一系列症状和功能严重程度的干预措施的风险效益比提供信息,并根据症状和功能严重程度而非人为的诊断分类更连贯地进行分诊和安排服务提供。