Liu Jian-Zhong, Fang Yuan, Pang Hongxi
College of Chemistry and Life Sciences, Zhejiang Normal University Jinhua, China.
College of Agronomy, Northwest A&F University Yangling, China.
Front Microbiol. 2016 Nov 30;7:1906. doi: 10.3389/fmicb.2016.01906. eCollection 2016.
(SMV) is one of the most devastating pathogens that cost huge economic losses in soybean production worldwide. Due to the duplicated genome, clustered and highly homologous nature of genes, as well as recalcitrant to transformation, soybean disease resistance studies is largely lagging compared with other diploid crops. In this review, we focus on the major advances that have been made in identifying both the virulence/avirulence factors of SMV and mapping of SMV resistant genes in soybean. In addition, we review the progress in dissecting the SMV resistant signaling pathways in soybean, with a special focus on the studies using virus-induced gene silencing. The soybean genome has been fully sequenced, and the increasingly saturated SNP markers have been identified. With these resources available together with the newly developed genome editing tools, and more efficient soybean transformation system, cloning SMV resistant genes, and ultimately generating cultivars with a broader spectrum resistance to SMV are becoming more realistic than ever.
大豆花叶病毒（SMV）是最具破坏性的病原体之一，在全球大豆生产中造成巨大经济损失。由于基因组重复、基因成簇且高度同源，以及转化困难，与其他二倍体作物相比，大豆抗病性研究在很大程度上滞后。在本综述中，我们重点关注在鉴定SMV的毒力/无毒力因子以及大豆中SMV抗性基因定位方面取得的主要进展。此外，我们回顾了剖析大豆中SMV抗性信号通路的进展，特别关注使用病毒诱导基因沉默的研究。大豆基因组已被完全测序，并且已鉴定出越来越多的饱和单核苷酸多态性（SNP）标记。有了这些资源，再加上新开发的基因组编辑工具和更高效的大豆转化系统，克隆SMV抗性基因并最终培育出对SMV具有更广泛抗性的品种比以往任何时候都更加现实。
