瑞典出现伴有脑病和感音神经性听力缺损的输入性拉沙热病例。
Imported Case of Lassa Fever in Sweden With Encephalopathy and Sensorineural Hearing Deficit.
作者信息
Grahn Anna, Bråve Andreas, Lagging Martin, Dotevall Leif, Ekqvist David, Hammarström Helena, Karlberg Helen, Lagerqvist Nina, Sansone Martina, Tegnell Anders, Ulleryd Peter, Studahl Marie
机构信息
Departments of Infectious Medicine.
Microbiology and.
出版信息
Open Forum Infect Dis. 2016 Sep 20;3(4):ofw198. doi: 10.1093/ofid/ofw198. eCollection 2016 Oct.
Abstract
We describe an imported case of Lassa fever with both encephalopathy and bilateral sensorineural hearing deficit. Absence of fever during hospitalization, initially nonspecific symptoms, and onset of hearing deficit in a late stage of disease probably contributed to delayed diagnosis (14 days after admittance to hospital). The pathogenesis of neurological manifestations of Lassa fever is poorly understood and no specific treatment was given. A total of 118 personnel had close contact with the patient, but no secondary cases occurred. This case highlights the importance of considering Lassa fever as a differential diagnosis in patients with recent travel to endemic areas.
摘要
我们描述了一例输入性拉沙热病例，该病例同时伴有脑病和双侧感音神经性听力减退。住院期间无发热，最初症状不具特异性，且在疾病后期出现听力减退，这些可能导致了诊断延迟（入院14天后确诊）。拉沙热神经表现的发病机制尚不清楚，且未给予特异性治疗。共有118名人员与该患者有过密切接触，但未出现二代病例。该病例凸显了对于近期前往疫区的患者，将拉沙热作为鉴别诊断的重要性。
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