利用旧病原体创造新疗法。

Exploiting Old Pathogens to Create New Therapeutics.

机构信息

Global Health Institute, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Vaud, Switzerland.

出版信息

Cell Host Microbe. 2016 Dec 14;20(6):705-707. doi: 10.1016/j.chom.2016.11.007.

DOI:10.1016/j.chom.2016.11.007

PMID:27978433

Abstract

Intestinal worms are well known for their potent immuno-modulatory capacity. In a recent study, Navarro et al. (2016) identify a secreted hookworm protein that can suppress allergic responses in both mice and humans. This represents an exciting strategy for treating chronic inflammatory disorders such as allergy.

摘要

肠道蠕虫以其强大的免疫调节能力而闻名。在最近的一项研究中，Navarro 等人（2016 年）鉴定出一种钩虫分泌的蛋白，它可以抑制小鼠和人类的过敏反应。这代表了治疗过敏等慢性炎症性疾病的一种令人兴奋的策略。