Bland Jeffrey
, , is the president and founder of the Personalized Lifestyle Medicine Institute in Seattle, Washington. He has been an internationally recognized leader in nutrition medicine for more than 25 years. Dr Bland is the cofounder of the Institute for Functional Medicine (IFM) and is chairman emeritus of IFM's Board of Directors. He is the author of the 2014 book The Disease Delusion: Conquering the Causes of Chronic Illness for a Healthier, Longer, and Happier Life.
Integr Med (Encinitas). 2016 Oct;15(5):14-16.
The gastrointestinal microbiome has become a topic of great interest in medicine in recent years. Genomic sequencing can now be done at a fraction of the cost of a few years ago, and this has allowed for the development and compilation of an extensive amount of data related to the species diversity of the human gastrointestinal microbiome.1 Studies have demonstrated that the intestinal microbiome is sensitive to the composition of the diet.2 It is also recognized that the composition of the microbiome can be altered rapidly in response to dietary changes, stress, chemical exposure, and exercise.3 Both the expanded understanding of the composition of the human microbiome and the ability to measure it through genomic analysis of the stool have resulted in clinicians frequently wanting to know what actionable conclusions can be taken away from an analysis of the gastrointestinal microbiome.
近年来,胃肠道微生物群已成为医学领域备受关注的话题。现在进行基因组测序的成本仅为几年前的一小部分,这使得与人类胃肠道微生物群物种多样性相关的大量数据得以开发和汇编。1 研究表明,肠道微生物群对饮食组成敏感。2 人们还认识到,微生物群的组成会因饮食变化、压力、化学物质暴露和运动而迅速改变。3 对人类微生物群组成的更深入了解以及通过粪便基因组分析来测量它的能力,使得临床医生常常想知道从胃肠道微生物群分析中可以得出哪些可采取行动的结论。