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子宫移植：一项系统综述。

Uterine transplantation: a systematic review.

作者信息

Ejzenberg Dani, Mendes Luana Regina Baratelli Carelli, Haddad Luciana Bertocco de Paiva, Baracat Edmund Chada, D'Albuquerque Luiz Augusto Carneiro, Andraus Wellington

机构信息

Departamento de Ginecologia, Faculdade de Medicina da Universidade de São Paulo, São Paulo/SP, Brasil.

Divisão de transplante de Órgãos Digestivos, Faculdade de Medicina da Universidade de São Paulo, São Paulo/SP, Brasil.

出版信息

Clinics (Sao Paulo). 2016 Nov 1;71(11):679-683. doi: 10.6061/clinics/2016(11)10.

DOI:10.6061/clinics/2016(11)10
PMID:27982170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5108169/
Abstract

Up to 15% of the reproductive population is infertile, and 3 to 5% of these cases are caused by uterine dysfunction. This abnormality generally leads women to consider surrogacy or adoption. Uterine transplantation, although still experimental, may be an option in these cases. This systematic review will outline the recommendations, surgical aspects, immunosuppressive drugs and reproductive aspects related to experimental uterine transplantation in women.

摘要

高达15%的育龄人群存在不孕问题，其中3%至5%的病例是由子宫功能障碍引起的。这种异常情况通常会使女性考虑代孕或领养。子宫移植尽管仍处于实验阶段，但在这些病例中可能是一种选择。本系统综述将概述与女性实验性子宫移植相关的建议、手术方面、免疫抑制药物及生殖方面的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50c9/5108169/2944bdfef1b1/cln-71-11-679-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50c9/5108169/2944bdfef1b1/cln-71-11-679-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50c9/5108169/2944bdfef1b1/cln-71-11-679-g001.jpg

相似文献

1
Uterine transplantation: a systematic review.子宫移植：一项系统综述。
Clinics (Sao Paulo). 2016 Nov 1;71(11):679-683. doi: 10.6061/clinics/2016(11)10.
2
Uterine transplantation: a promising surrogate to surrogacy?子宫移植：代孕的一种有前途的替代方案？
Ann N Y Acad Sci. 2011 Mar;1221:47-53. doi: 10.1111/j.1749-6632.2011.05952.x.
3
[Uterus transplantation. Current situation].[子宫移植。现状]
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Uterine transplantation in primates: a mini-review of the literature.灵长类动物的子宫移植：文献综述
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Description and evaluation of experimental models for uterine transplantation in pigs.猪子宫移植实验模型的描述与评估
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Experimental uterus transplantation.实验性子宫移植。
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Uterine transplantation research: laboratory protocols for clinical application.子宫移植研究：临床应用的实验室方案。
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Uterine transplantation: what else needs to be done before it can become a reality?子宫移植：在其成为现实之前还需要做些什么？
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Transplantation. 2018 Apr;102(4):569-577. doi: 10.1097/TP.0000000000002035.

引用本文的文献

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Diseases. 2025 May 15;13(5):152. doi: 10.3390/diseases13050152.
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Motivations for uterus transplantation in women with absolute uterine factor infertility: A systematic review of the literature.绝对子宫因素不孕症女性子宫移植的动机：文献系统综述
Clinics (Sao Paulo). 2025 Apr 13;80:100646. doi: 10.1016/j.clinsp.2025.100646. eCollection 2025.
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Comprehensive Review of Fluorescence Applications in Gynecology.妇科荧光应用的综合综述

本文引用的文献

1
One uterus bridging three generations: first live birth after mother-to-daughter uterus transplantation.一个子宫连接三代人：母女子宫移植后的首例活产
Fertil Steril. 2016 Aug;106(2):261-6. doi: 10.1016/j.fertnstert.2016.04.001. Epub 2016 Apr 25.
2
Uterus transplantation: current progress and future prospects.子宫移植：现状与未来展望。
Int J Womens Health. 2016 Feb 5;8:43-51. doi: 10.2147/IJWH.S75635. eCollection 2016.
3
Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation.
J Clin Med. 2021 Sep 25;10(19):4387. doi: 10.3390/jcm10194387.
4
Uterus Transplant: Does It Have Legs?子宫移植：可行吗？
J Obstet Gynaecol India. 2017 Oct;67(5):309-312. doi: 10.1007/s13224-017-1037-9. Epub 2017 Jul 21.
5
What are the Possibilities of Uterine Transplantation in Transgender Patients?子宫移植在跨性别患者中的可能性有哪些？
Rev Bras Ginecol Obstet. 2017 Oct;39(10):521-522. doi: 10.1055/s-0037-1606321. Epub 2017 Aug 28.
系统评价和荟萃分析议定书的首选报告项目（PRISMA-P）2015：详细说明和解释。
BMJ. 2015 Jan 2;350:g7647. doi: 10.1136/bmj.g7647.
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Uterus transplantation trial: 1-year outcome.子宫移植试验：1年结果。
Fertil Steril. 2015 Jan;103(1):199-204. doi: 10.1016/j.fertnstert.2014.09.024. Epub 2014 Oct 22.
5
Livebirth after uterus transplantation.子宫移植后活产。
Lancet. 2015 Feb 14;385(9968):607-616. doi: 10.1016/S0140-6736(14)61728-1. Epub 2014 Oct 6.
6
Pregnancies in liver and kidney transplant recipients: a review of the current literature and recommendation.肝、肾移植受者的妊娠：对当前文献的回顾与建议。
Best Pract Res Clin Obstet Gynaecol. 2014 Nov;28(8):1123-36. doi: 10.1016/j.bpobgyn.2014.07.021. Epub 2014 Aug 8.
7
Disparities in cervical and breast cancer mortality in Brazil.巴西宫颈癌和乳腺癌死亡率的差异。
Rev Saude Publica. 2014 Jun;48(3):459-67. doi: 10.1590/s0034-8910.2014048005214.
8
First clinical uterus transplantation trial: a six-month report.首例临床子宫移植试验：6 个月报告。
Fertil Steril. 2014 May;101(5):1228-36. doi: 10.1016/j.fertnstert.2014.02.024. Epub 2014 Feb 27.
9
Clinical pregnancy after uterus transplantation.子宫移植后的临床妊娠。
Fertil Steril. 2013 Nov;100(5):1358-63. doi: 10.1016/j.fertnstert.2013.06.027. Epub 2013 Jul 3.
10
Current status of uterus transplantation in primates and issues for clinical application.灵长类动物子宫移植的现状及临床应用问题。
Fertil Steril. 2013 Jul;100(1):280-94. doi: 10.1016/j.fertnstert.2013.03.004. Epub 2013 Apr 1.