Latella Christopher, Hendy Ashlee M, Pearce Alan J, VanderWesthuizen Dan, Teo Wei-Peng
School of Exercise and Nutrition Sciences, Deakin University Burwood, VIC, Australia.
Melbourne School of Health Sciences, The University of Melbourne Melbourne, VIC, Australia.
Front Hum Neurosci. 2016 Dec 1;10:607. doi: 10.3389/fnhum.2016.00607. eCollection 2016.
: The current understanding of acute neurophysiological responses to resistance training remains unclear. Therefore, we aimed to compare the time-course of acute corticospinal responses following a single-session heavy strength training (HST) of the biceps brachii (BB) muscle and provide quantifiable evidence based on the super-compensation model in an applied setting. : Fourteen participants completed a counter-balanced, cross-over study that consisted of a single HST session (5 sets × 3 repetition maximum [RM]) of the BB and a control session (CON). Single- and paired-pulse transcranial magnetic stimulation (TMS) was used to measure changes in motor-evoked potential (MEP) amplitude, intra-cortical facilitation (ICF), short-interval intra-cortical inhibition (SICI) and long-interval intra-cortical inhibition (LICI). Additionally, maximal muscle compound wave (M) and maximal voluntary isometric contraction (MVIC) of the BB were taken. All measures were taken at baseline, immediately post and at 10, 20, 30 min and 1, 2, 6, 24, 48 and 72 h post-training. : A significant reduction in MEP amplitude was observed immediately post training ( = 0.001), while MVIC ( < 0.001) and M ( = 0.047) were reduced for up to 30 min post-training. An increase in MVIC ( < 0.001) and M ( = 0.047) was observed at 6 h, while an increase in MEP amplitude ( = 0.014) was only observed at 48 and 72 h. No changes in SICI, ICF and LICI were observed. : Our results suggest that: (1) acute changes in corticospinal measures returned to baseline in a shorter timeframe than the current super-compensation model (24-48 h) and (2) changes in corticospinal excitability post-HST may be modulated "downstream" of the primary motor cortex (M1).
目前对阻力训练急性神经生理反应的理解仍不明确。因此，我们旨在比较肱二头肌单次高强度力量训练（HST）后急性皮质脊髓反应的时间进程，并在实际应用中基于超量恢复模型提供可量化的证据。14名参与者完成了一项平衡交叉研究，该研究包括一次肱二头肌的HST训练（5组×3次最大重复量[RM]）和一次对照训练（CON）。使用单脉冲和双脉冲经颅磁刺激（TMS）来测量运动诱发电位（MEP）幅度、皮质内易化（ICF）、短间隔皮质内抑制（SICI）和长间隔皮质内抑制（LICI）的变化。此外，还测量了肱二头肌的最大肌肉复合波（M）和最大自主等长收缩（MVIC）。所有测量均在基线、训练后即刻以及训练后10、20、30分钟和1、2、6、24、48和72小时进行。训练后即刻观察到MEP幅度显著降低（P = 0.001），而MVIC（P < 0.001）和M（P = 0.047）在训练后长达30分钟内降低。在6小时时观察到MVIC（P < 0.001）和M（P = 0.047）增加，而仅在48和72小时观察到MEP幅度增加（P = 0.014）。未观察到SICI、ICF和LICI的变化。我们的结果表明：（1）皮质脊髓测量的急性变化在比当前超量恢复模型（24 - 48小时）更短的时间内恢复到基线，（2）HST后皮质脊髓兴奋性的变化可能在初级运动皮层（M1）的“下游”受到调节。
