Pinkham Amy E, Harvey Philip D, Penn David L
School of Behavioral and Brain Sciences, The University of Texas at Dallas, Richardson, TX, 75080; Department of Psychiatry, University of Texas Southwestern Medical School, Dallas, TX, 75390.
Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, 33136; Research Service, Bruce W Carter VA Medical Center, Miami, FL, 33125.
Schizophr Res Cogn. 2016 Mar;3:33-38. doi: 10.1016/j.scog.2015.11.002. Epub 2016 Jan 13.
Paranoia is a common symptom of schizophrenia that may be related to how individuals process and respond to social stimuli. Previous investigations support a link between increased paranoia and greater social cognitive impairments, but these studies have been limited to single domains of social cognition, and no studies have examined how paranoia may influence functional outcome. Data from 147 individuals with schizophrenia were used to examine whether actively paranoid and non-paranoid individuals with schizophrenia differ in social cognition and functional outcomes. On measures assessing social cognitive bias, paranoid individuals endorsed more hostile and blaming attributions and identified more faces as untrustworthy; however, paranoid and non-paranoid individuals did not differ on emotion recognition and theory of mind tasks assessing social cognitive ability. Likewise, paranoid individuals showed greater impairments in real-world interpersonal relationships and social acceptability as compared to non-paranoid patients, but these differences did not extend to performance based tasks assessing functional capacity and social competence. These findings isolate specific social cognitive disparities between paranoid and non-paranoid subgroups and suggest that paranoia may exacerbate the social dysfunction that is commonly experienced by individuals with schizophrenia.
妄想症是精神分裂症的常见症状,可能与个体处理和应对社会刺激的方式有关。先前的调查支持妄想症增加与更严重的社会认知障碍之间存在联系,但这些研究仅限于社会认知的单一领域,且尚无研究考察妄想症如何影响功能结局。来自147名精神分裂症患者的数据被用于检验患有精神分裂症的主动妄想症患者和非妄想症患者在社会认知和功能结局方面是否存在差异。在评估社会认知偏差的测量中,妄想症患者认可更多敌意和指责性归因,并将更多面孔识别为不可信任;然而,在评估社会认知能力的情绪识别和心理理论任务上,妄想症患者和非妄想症患者并无差异。同样,与非妄想症患者相比,妄想症患者在现实人际关系和社会可接受性方面表现出更大的障碍,但这些差异并未扩展到基于表现的评估功能能力和社会能力的任务中。这些发现揭示了妄想症和非妄想症亚组之间特定的社会认知差异,并表明妄想症可能会加剧精神分裂症患者普遍经历的社会功能障碍。