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希腊一家医院中同时产NDM-1和VIM-1金属β-内酰胺酶的11型肺炎克雷伯菌的出现。

Emergence of sequence type 11 Klebsiella pneumoniae coproducing NDM-1 and VIM-1 metallo-β-lactamases in a Greek hospital.

作者信息

Papagiannitsis C C, Malli E, Florou Z, Sarrou S, Hrabak J, Mantzarlis K, Zakynthinos E, Petinaki E

机构信息

Department of Microbiology, University Hospital of Larissa, Larissa, Greece; Biomedical Center, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic.

Department of Microbiology, University Hospital of Larissa, Larissa, Greece.

出版信息

Diagn Microbiol Infect Dis. 2017 Mar;87(3):295-297. doi: 10.1016/j.diagmicrobio.2016.12.008. Epub 2016 Dec 14.

DOI:10.1016/j.diagmicrobio.2016.12.008
PMID:27993422
Abstract

Sequence type 11 Klebsiella pneumoniae, coproducing NDM-1 and VIM-1 metallo-β-lactamases, were isolated in a Greek hospital. bla was part of a Tn125 derivative, located on an ~90-kb plasmid similar to the NDM-1-encoding plasmid pB-3002cz. bla was located in an In-e541-like integron, carried on a multireplicon (IncA/C and IncR) plasmid of ~180kb.

摘要

在一家希腊医院分离出了产NDM-1和VIM-1金属β-内酰胺酶的11型肺炎克雷伯菌。bla是Tn125衍生物的一部分，位于一个约90kb的质粒上，该质粒类似于编码NDM-1的质粒pB-3002cz。bla位于一个In-e541样整合子中，该整合子位于一个约180kb的多复制子（IncA/C和IncR）质粒上。

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