Simon C, Allou N, Schlossmacher P, Gendry T, Delay L, Gazaille V
Centre hospitalier Félix-Guyon, CHU de la Réunion, allée des Topazes, 97400 Saint-Denis, Réunion.
Groupe hospitalier sud Réunion, CHU de la Réunion, avenue du président Miterrand, 97410 Saint-Pierre, Réunion.
Rev Pneumol Clin. 2017 Apr;73(2):75-80. doi: 10.1016/j.pneumo.2016.10.003. Epub 2016 Dec 16.
Lung transplantation (LT) is a therapeutic option for patients with terminal respiratory failure and high risk of mortality in two years. Until now, this activity is not performed in Reunion Island. The candidate potential are thus directed to the metropolitan reference centres causing logistics and financials constraints. This work presents a current situation of the pulmonary transplantation in Reunion Island. This retrospective study includes patients from Reunion Island with respiratory insufficiency who have been transferred to metropolitan centres to apply to LT. The selection was made from January, 2005 till May, 2015. Twenty-nine patients included, aged from 14 to 64 years, were transferred to metropolitan France: 13 patients with cystic fibrosis, 13 patients with pulmonary fibrosis, 1 patients with bronchiectasis, 1 patient with chronic obstructive pulmonary disease (COPD) and 1 patient with pulmonary arterial hypertension. Fifteen patients underwent LT (4 live in Reunion Island, 5 live in metropolitan France and 6 are dead), 1 patient is alive on waiting list, 3 died on the waiting list, 7 patients were refused for transplantation and 3 patients are lost to follow-up. The number of patients transferred for LT increases over 10 years with a maximal incidence in 2013 of 7 repatriated patients including 3 transplanted patients. LT could be performed in half of our patients with possible come back and follow-up on Reunion Island. Indications follow the current trends except an under representation of COPD.
肺移植（LT）是终末期呼吸衰竭且两年内死亡风险高的患者的一种治疗选择。到目前为止，留尼汪岛尚未开展此项业务。因此，潜在的候选患者被送往法国本土的参考中心，这带来了后勤和财务方面的限制。这项工作展示了留尼汪岛肺移植的现状。这项回顾性研究纳入了留尼汪岛患有呼吸功能不全并已被转至法国本土中心申请肺移植的患者。研究对象的选取时间为2005年1月至2015年5月。共纳入29名年龄在14岁至64岁之间的患者，他们被转至法国本土：13例囊性纤维化患者、13例肺纤维化患者、1例支气管扩张症患者、1例慢性阻塞性肺疾病（COPD）患者和1例肺动脉高压患者。15例患者接受了肺移植（4例现居留尼汪岛，5例现居法国本土，6例已死亡）；1例患者在等待名单上存活；3例在等待名单上死亡；7例患者被拒绝移植；3例患者失访。10年间，转至法国本土申请肺移植的患者数量有所增加，2013年达到最高值，有7名患者被遣返回国，其中3例接受了移植。一半的患者有可能在留尼汪岛接受肺移植并进行后续随访。除COPD患者比例较低外，各项指征均符合当前趋势。
