瑞士一例可能通过输血传播恰加斯病的病例。
A Case of Possible Chagas Transmission by Blood Transfusion in Switzerland.
作者信息
Ries Judith, Komarek Adriana, Gottschalk Jochen, Brand Birgit, Amsler Lorenz, Jutzi Markus, Frey Beat M
机构信息
Blood Transfusion Service Zurich, Zurich, Switzerland.
Division of Hematology, University Hospital Zurich, Zurich, Switzerland, Berne, Switzerland.
出版信息
Transfus Med Hemother. 2016 Nov;43(6):415-417. doi: 10.1159/000446264. Epub 2016 Nov 4.
BACKGROUND
Transfusion-transmitted Chagas disease has been reported from endemic countries in Latin America. Switzerland is a non-endemic country but high prevalence of antibodies against was found among immigrants. Immigrants may participate in blood donation; therefore, risk-adapted anti- screening for blood donors was implemented in Switzerland in 2013.
METHODS
Between January 2013 and July 2015, 1 out of 1,183 at-risk donors, tested at Blood Transfusion Service Zurich, was found anti- IgG-positive.
RESULTS AND CONCLUSION
Out of 54 donations given by the index donor (ID), we identified 77 blood products which were delivered to hospitals. Archived serum samples from the donations given during the prior 5 years were available for retrospective testing. All samples from ID revealed positive findings for anti- IgG. Donor-triggered look-back procedure identified a 70-year-old male recipient of a platelet concentrate (PC) donated by ID. The recipient succumbed of acute infection 2 years after transfusion of the PC.
背景
拉丁美洲的一些流行国家已报告了输血传播的恰加斯病。瑞士是一个非流行国家，但在移民中发现抗 抗体的高流行率。移民可能会参与献血；因此，瑞士于2013年对献血者实施了风险适应性抗 筛查。
方法
2013年1月至2015年7月期间，在苏黎世输血服务中心接受检测的1183名高危献血者中，有1人抗 IgG呈阳性。
结果与结论
在索引献血者（ID）提供的54次献血中，我们确定有77份血液制品被送往医院。可获得前5年献血时存档的血清样本用于回顾性检测。ID的所有样本抗 IgG检测均呈阳性。由献血者触发的追溯程序确定了一名70岁男性接受了ID捐献的血小板浓缩物（PC）。该受血者在输注PC两年后死于急性 感染。
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