Mingos Mark, Howard Stephanie, Giacalone Nicholas, Kozono David, Jacene Heather
Department of Imaging, Dana-Farber Cancer Institute and Department of Radiology, Brigham and Women's Hospital, 450 Brookline Avenue, Boston, MA 02215 USA.
Department of Radiation Oncology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115 USA.
Nucl Med Mol Imaging. 2016 Dec;50(4):358-361. doi: 10.1007/s13139-015-0385-6. Epub 2015 Dec 9.
A patient with newly diagnosed right lung cancer had transient F-fluorodeoxyglucose (FDG)-avid left axillary lymph nodes and intense splenic FDG uptake on positron emission tomography (PET)/computed tomography (CT). History revealed that the patient received a left-sided influenza vaccine 2-3 days before the examination. Although inflammatory FDG uptake in ipsilateral axillary nodes is reported, to our knowledge, this is the first report of visualization of the systemic immune response in the spleen related to the influenza vaccination on FDG-PET/CT. The history, splenic uptake and time course on serial FDG-PET/CT helped to avoid a false-positive interpretation for progressing lung cancer and alteration of the radiation therapy plan.
一名新诊断为右肺癌的患者在正电子发射断层扫描（PET）/计算机断层扫描（CT）上出现短暂的氟脱氧葡萄糖（FDG）摄取阳性的左腋窝淋巴结以及脾脏FDG摄取增强。病史显示该患者在检查前2 - 3天接种了左侧流感疫苗。虽然已有同侧腋窝淋巴结炎性FDG摄取的报道，但据我们所知，这是首次关于流感疫苗接种相关的脾脏系统性免疫反应在FDG - PET/CT上显影的报道。病史、脾脏摄取情况以及连续FDG - PET/CT的时间进程有助于避免对进展期肺癌的假阳性解读以及放疗计划的改变。
