Liu Cheng, Guo Jun, Cui Qiu, Li Dingfeng, Zeng Yanjun
Department of Orthopedics, The Affiliated Hospital of Academy of Military Medical Sciences, PLA 307th Hospital, Beijing, 100071 China.
Beijing University of Technology, 100 Pingleyuan, Chaoyang District, Beijing, 100022 China.
Springerplus. 2016 Dec 1;5(1):2058. doi: 10.1186/s40064-016-3727-7. eCollection 2016.
The incidence of subclinical hemophilic arthritis is low, with this case reports and literature review, we hope clinicians could pay more attention to the diagnosis of subclinical hemophilic arthritis and prevent the misdiagnosis and mistreatment.
We analyzed the imaging feature, and therapy of a subclinical hemophilia case with hip lesion by reporting its clinical manifestations, imaging features and therapy procedure, and reviewing literatures.
Hemophilia is a sex-linked recessive hereditary hemorrhagic disease, and the pathogenesis of subclinic hemophilia is concealed, which often involves joint lesion. The imaging of joint lesion of hemophilia cases is typical, which facilitates the differential diagnosis with other joint diseases. The current treatment is mainly supplementary or replacement therapy.
Hemophilic arthritis cases, especially the mild or subclinical cases without family history and with an older age of onset, are not common. The disease should be further understood, and early diagnosis and treatment is crucial to prevent the progressive development of joint diseases.
亚临床型血友病性关节炎的发病率较低,通过本病例报告及文献复习,希望临床医生能更加重视亚临床型血友病性关节炎的诊断,防止误诊和误治。
我们通过报告1例髋关节病变的亚临床型血友病病例的临床表现、影像学特征及治疗过程,并复习文献,分析其影像学特点及治疗方法。
血友病是一种X连锁隐性遗传性出血性疾病,亚临床型血友病的发病机制隐匿,常累及关节病变。血友病病例关节病变的影像学表现具有特征性,有助于与其他关节疾病进行鉴别诊断。目前的治疗主要是补充或替代疗法。
血友病性关节炎病例,尤其是无家族史、发病年龄较大的轻型或亚临床型病例并不常见。应进一步认识该疾病,早期诊断和治疗对于预防关节疾病的进展至关重要。