Cassiède Marc, Nair Sindhu, Dueck Meghan, Mino James, McKay Ryan, Mercier Pascal, Quémerais Bernadette, Lacy Paige
Pulmonary Research Group, Department of Medicine, University of Alberta, Edmonton, AB, Canada; Department of Chemistry, University of Alberta, Edmonton, AB, Canada; National High Field NMR Centre (NANUC), University of Alberta, Edmonton, AB, Canada.
Data Brief. 2016 Dec 7;10:227-229. doi: 10.1016/j.dib.2016.11.101. eCollection 2017 Feb.
The data in this article are related to the research entitled, "Assessment of H NMR-based metabolomics analysis for normalization of urinary metals against creatinine" (M. Cassiède, S. Nair, M. Dueck, J. Mino, R. McKay, P. Mercier, B. Quémerais, P. Lacy, 2016) [1]. This article describes the analysis of urinary metabolites in normal, healthy individuals by H NMR-based metabolomics. NMR spectra of urine samples typically contain hundreds of peaks that must be carefully screened for reproducibility and detectability. An important requirement in the screening of appropriate urinary metabolites is to ensure that they are reproducibly detected. In our study, we applied the peak profiles of 151 known urinary metabolites to 10 normal human urine samples and found that 50 metabolites were reproducibly measured between 600 and 700 MHz magnets in the same samples. The data set has been made publicly available to enable critical or extended analysis.
本文中的数据与题为《基于氢核磁共振代谢组学分析对尿金属与肌酐进行标准化评估》（M. Cassiède、S. Nair、M. Dueck、J. Mino、R. McKay、P. Mercier、B. Quémerais、P. Lacy，2016年）的研究相关[1]。本文描述了通过基于氢核磁共振的代谢组学对正常健康个体尿液代谢物的分析。尿液样本的核磁共振谱通常包含数百个峰，必须对其进行仔细筛选以确保可重复性和可检测性。筛选合适的尿液代谢物的一个重要要求是确保它们能够被重复检测。在我们的研究中，我们将151种已知尿液代谢物的峰谱应用于10份正常人类尿液样本，发现在相同样本中，在600至700兆赫的磁体之间能够重复测量50种代谢物。该数据集已公开提供，以便进行批判性或扩展性分析。
