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躯体严重程度对神经性厌食症长期死亡率的影响。

Impact of somatic severity on long-term mortality in anorexia nervosa.

作者信息

Stheneur Chantal, Ali Aminata, Tric Laurent, Curt Florence, Hubert Tamara, Godart Nathalie

机构信息

Adolescent Medicine Unit, Department of Pediatrics, Sainte Justine Hospital, 3175 chemin de la cote Sainte Catherine, Montreal, QC, H3T 1C5, Canada.

CESP-INSERM U1178, University Paris-Sud, Université Sorbonne Paris Cité, 75014, Paris, France.

出版信息

Eat Weight Disord. 2017 Jun;22(2):285-289. doi: 10.1007/s40519-016-0346-9. Epub 2016 Dec 19.

DOI:10.1007/s40519-016-0346-9
PMID:27995488
Abstract

PURPOSE

Anorexia nervosa (AN) is a severe pathology on account of the high levels of associated morbidity and mortality. This study aimed to assess whether time in somatic intensive care unit, justified by a patient's somatic condition in the course of hospital care, has any relationship with patient outcome in terms of mortality in the long term.

METHODS

195 patients were hospitalised for AN between April 1996 and May 2002, 97 were re-assessed 9 years later on average.

RESULTS

Out of 195 patients hospitalised for AN between April 1996 and May 2002, 29 had required transfer to intensive care. Mortality at 9 years was 20 times higher in the group having been transferred to intensive care, irrespective of the duration of follow-up.

CONCLUSION

The clinical seriousness of the somatic condition during hospitalisation for AN is a risk factor for excess mortality in the medium term.

摘要

目的

神经性厌食症(AN)是一种严重的病症,因其伴随的高发病率和死亡率。本研究旨在评估在医院护理过程中因患者躯体状况而入住躯体重症监护病房的时间,与长期死亡率方面的患者预后是否存在任何关联。

方法

1996年4月至2002年5月期间,195例因AN住院的患者,平均9年后对其中97例进行了重新评估。

结果

在1996年4月至2002年5月期间因AN住院的195例患者中,29例需要转至重症监护病房。转至重症监护病房的组在9年时的死亡率高出20倍,与随访时间无关。

结论

AN住院期间躯体状况的临床严重性是中期额外死亡的一个危险因素。

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本文引用的文献

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Mortality in Women With Anorexia Nervosa: The Role of Comorbid Psychiatric Disorders.神经性厌食症女性的死亡率:共病精神障碍的作用。
Psychosom Med. 2016 Oct;78(8):910-919. doi: 10.1097/PSY.0000000000000342.
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Refeeding Low Weight Hospitalized Adolescents With Anorexia Nervosa: A Multicenter Randomized Controlled Trial.重新喂养低体重住院神经性厌食青少年:一项多中心随机对照试验。
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Cardiovascular complications of anorexia nervosa: A systematic review.
CD4 T细胞上CXCR4的表达可预测神经性厌食症女性青少年的身体成分参数。
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Nutrients. 2022 Jul 19;14(14):2951. doi: 10.3390/nu14142951.
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Increased risk of somatic diseases following anorexia nervosa in a controlled nationwide cohort study.在一项全国性对照队列研究中,神经性厌食症后躯体疾病风险增加。
Int J Eat Disord. 2022 Jun;55(6):754-762. doi: 10.1002/eat.23718. Epub 2022 Apr 22.
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Health in adulthood after severe anorexia nervosa in adolescence: a study of exposed and unexposed women.青春期重度神经性厌食症后成年期的健康:暴露组和未暴露组女性的研究。
Eat Weight Disord. 2021 Jun;26(5):1389-1397. doi: 10.1007/s40519-020-00940-5. Epub 2020 Jun 23.
神经性厌食症的心血管并发症:一项系统综述。
Int J Eat Disord. 2016 Mar;49(3):238-48. doi: 10.1002/eat.22481. Epub 2015 Dec 29.
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Prognostic factors and outcome in anorexia nervosa: a follow-up study.神经性厌食症的预后因素与结局:一项随访研究
Eat Weight Disord. 2016 Mar;21(1):73-82. doi: 10.1007/s40519-015-0211-2. Epub 2015 Aug 8.
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Medical complications of anorexia nervosa and their treatments: an update on some critical aspects.神经性厌食症的医学并发症及其治疗:一些关键方面的最新进展
Eat Weight Disord. 2015 Dec;20(4):419-25. doi: 10.1007/s40519-015-0202-3. Epub 2015 Jul 3.
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Follow-up mortality study of compulsorily treated patients with anorexia nervosa.强制性治疗的神经性厌食症患者的随访死亡率研究。
Int J Eat Disord. 2015 Nov;48(7):860-5. doi: 10.1002/eat.22377. Epub 2014 Dec 26.
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Eat Weight Disord. 2014 Mar;19(1):49-59. doi: 10.1007/s40519-013-0065-4.
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Body mass index and in-hospital mortality in anorexia nervosa: data from the Japanese Diagnosis Procedure Combination database.体质量指数与神经性厌食症患者院内死亡率:来自日本诊断程序组合数据库的数据。
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