Zhan Ruoyu, Pan Yutong, Manghnani Purnima Naresh, Liu Bin
School of Materials Science and Engineering, Tongji University, 4800 Caoan Road, Shanghai, 201804, China.
Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, 117585, Singapore.
Macromol Biosci. 2017 May;17(5). doi: 10.1002/mabi.201600433. Epub 2016 Dec 20.
Aggregation-caused quenching (ACQ) is a general phenomenon that is faced by traditional fluorescent polymers. Aggregation-induced emission (AIE) is exactly opposite to ACQ. AIE molecules are almost nonemissive in their molecularly dissolved state, but they can be induced to show high fluorescence in the aggregated or solid state. Incorporation of AIE phenomenon into polymer design has yielded various polymers with AIE characteristics. In this review, the recent progress of AIE polymers for biological applications is summarized.
聚集诱导猝灭(ACQ)是传统荧光聚合物普遍面临的一种现象。聚集诱导发光(AIE)则与ACQ完全相反。AIE分子在分子溶解状态下几乎不发光,但在聚集态或固态时可被诱导表现出高荧光。将AIE现象引入聚合物设计已产生了各种具有AIE特性的聚合物。在本综述中,总结了AIE聚合物在生物应用方面的最新进展。