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中国中年及以上人群的身高与高血压患病率。

Height and prevalence of hypertension in a middle-aged and older Chinese population.

机构信息

MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Department of Maternal and Child Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

出版信息

Sci Rep. 2016 Dec 21;6:39480. doi: 10.1038/srep39480.

DOI:10.1038/srep39480
PMID:28000763
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5175189/
Abstract

Evidence from epidemiological studies reported that height was inversely associated with cardiovascular diseases, but the association between height and hypertension was unclear. The purpose of this study was to explore the association between height and blood pressure or prevalence of hypertension in a middle-aged and older Chinese population. A total of 33,197 participants aged 37 to 94 years were recruited from the Dongfeng-Tongji cohort study in Hubei province, China. All participants completed baseline questionnaires, medical examinations and provided blood samples. Hypertension was define as a systolic blood pressure (SBP) over 140 mmHg or/and a diastolic blood pressure (DBP) over 90 mmHg, or current use of antihypertensive medication, or participants with self-reported physician diagnosis of hypertension. Multivariate linear and logistic regression models were used. The prevalence of hypertension was 69.1% for men and 58.0% for women. Pulse pressure (PP) and SBP, but not DBP decreased linearly with increasing height among men and women. Comparing the highest with the shortest quartile of height, the multivariate-adjusted odds ratios were 0.80 (95% confidence interval, 0.71, 0.91) for men and 0.83 (0.74, 0.92) for women. In conclusion, height was associated with reduced SBP, PP and prevalence of hypertension in a middle-aged and older Chinese population.

摘要

来自流行病学研究的证据表明,身高与心血管疾病呈负相关,但身高与高血压之间的关系尚不清楚。本研究旨在探讨中国中年及以上人群的身高与血压或高血压患病率之间的关系。

共有 33197 名年龄在 37 至 94 岁的参与者来自中国湖北省的东风-同济队列研究。所有参与者均完成了基线问卷调查、体检并提供了血液样本。高血压定义为收缩压(SBP)超过 140mmHg 或/和舒张压(DBP)超过 90mmHg,或正在使用降压药物,或参与者自述有医生诊断的高血压。采用多元线性和逻辑回归模型。男性高血压患病率为 69.1%,女性为 58.0%。男性和女性的脉压(PP)和 SBP 随身高的增加呈线性下降,但 DBP 则不然。与身高最高的四分之一相比,身高最矮的四分之一的男性和女性的多变量校正比值比分别为 0.80(95%置信区间,0.71,0.91)和 0.83(0.74,0.92)。

总之,身高与中国中年及以上人群的 SBP、PP 和高血压患病率降低有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e612/5175189/0a8d6e7ba8d3/srep39480-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e612/5175189/7135b981f6cb/srep39480-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e612/5175189/0a8d6e7ba8d3/srep39480-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e612/5175189/7135b981f6cb/srep39480-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e612/5175189/0a8d6e7ba8d3/srep39480-f2.jpg

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