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乌干达西南部农村地区献血者的ABO和恒河猴(D)血型分布:一项回顾性研究。

ABO and Rhesus (D) blood group distribution among blood donors in rural south western Uganda: a retrospective study.

作者信息

Apecu Richard Onyuthi, Mulogo Edgar M, Bagenda Fred, Byamungu Andrew

机构信息

Department of Medical Laboratory Sciences, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.

Department of Community Health, Mbarara University of Science and Technology, P.O. Box 1410, Mbarara, Uganda.

出版信息

BMC Res Notes. 2016 Dec 21;9(1):513. doi: 10.1186/s13104-016-2299-5.

Abstract

BACKGROUND

In Uganda, geographical distribution of blood groups and Rhesus (D) factor varies across the country. The aim of this study was to examine the distribution of these groups among voluntary blood donors in rural southwestern Uganda.

RESULTS

Twenty-three thousand five hundred four (23,504) blood donors were included in the study. The donors had a mean age of 21 years (SD ± 5.7) and were mainly male (73%). The distribution of ABO blood group was; blood group O (50.3%); blood group A (24.6%); blood group B (20.7%) and blood group AB (4.5%). The proportions of Rhesus (D) positive and Rhesus (D) negative were 98 and 2% respectively. The proportion of non-adult donors (<18 years) was significantly higher among the female than the male donors (p value <0.001). A significantly higher proportion of males than females were Rhesus (D) negative (p-value <0.001). No significant relationship was found between age and blood group distribution.

CONCLUSION

The sequence of ABO distribution among the rural population in southwestern Uganda is; O > A > B > AB, with males as the predominant donors. The frequency of Rhesus (D) negative is very low in rural southwestern Ugandan and is mainly among males. The blood bank services in southwestern Uganda need to develop innovative strategies targeting female donors who are more likely to boost blood stocks in the region.

摘要

背景

在乌干达,血型和恒河猴(D)因子的地理分布在全国各不相同。本研究的目的是调查这些血型在乌干达西南部农村地区自愿献血者中的分布情况。

结果

本研究纳入了23504名献血者。这些献血者的平均年龄为21岁(标准差±5.7),主要为男性(73%)。ABO血型分布为:O型血(50.3%);A型血(24.6%);B型血(20.7%);AB型血(4.5%)。恒河猴(D)阳性和恒河猴(D)阴性的比例分别为98%和2%。女性非成年献血者(<18岁)的比例显著高于男性献血者(p值<0.001)。恒河猴(D)阴性的男性比例显著高于女性(p值<0.001)。未发现年龄与血型分布之间存在显著关系。

结论

乌干达西南部农村人口中ABO血型分布顺序为:O>A>B>AB,男性为主要献血者。在乌干达西南部农村地区,恒河猴(D)阴性的频率非常低,且主要集中在男性中。乌干达西南部的血库服务需要制定创新策略,以吸引更有可能增加该地区血液储备的女性献血者。

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