Oliveira-Maia Albino J, Andrade Isabel, Barahona-Corrêa J Bernardo
Department of Psychiatry and Mental Health, Centro Hospitalar de Lisboa Ocidental and NOVA Medical School | Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisboa, Portugal.
Champalimaud Research and Clinical Centre, Champalimaud Centre for the Unknown, Lisboa, Portugal.
BMJ Case Rep. 2016 Dec 21;2016:bcr2016216825. doi: 10.1136/bcr-2016-216825.
We describe a case of coeliac disease that was diagnosed in the psychiatry inpatient unit of a general hospital. The patient was admitted due to suicidal behaviours and developed an agitated catatonic state while in the inpatient psychiatry unit. An extensive diagnostic study allowed for the diagnosis of coeliac disease and while her state was unresponsive to antidepressants, anxiolytics, antipsychotics and electroconvulsive therapy, the patient improved significantly when a gluten-free diet was started. While it is well known that, occasionally, gluten sensitivity and coeliac disease can present as brain gluten sensitivity, such cases are typically characterised by motor and/or cognitive symptoms and by white matter abnormalities. Psychiatric presentations of these conditions have only rarely been reported.
我们描述了一例在综合医院精神科住院部被诊断出患有乳糜泻的病例。该患者因自杀行为入院,在精神科住院期间发展为激越性紧张症状态。广泛的诊断性检查得以诊断出乳糜泻,尽管她的状态对抗抑郁药、抗焦虑药、抗精神病药和电休克治疗均无反应,但开始无麸质饮食后患者有了显著改善。虽然众所周知,偶尔麸质敏感性和乳糜泻可表现为脑麸质敏感性,但此类病例通常以运动和/或认知症状以及白质异常为特征。这些病症的精神科表现仅有极少的报道。