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黄斑下出血的气体置换

Pneumatic displacement of submacular haemorrhage.

作者信息

Abdelkader Ehab, Yip Kay P, Cornish Kurt Spiteri

机构信息

Aberdeen Royal Infirmary, Aberdeen, UK; KKESH, Riyadh, Saudi Arabia.

Aberdeen Royal Infirmary, Aberdeen, UK; Worcester Royal Hospital, Charles Hastings Way, Worcester, UK.

出版信息

Saudi J Ophthalmol. 2016 Oct-Dec;30(4):221-226. doi: 10.1016/j.sjopt.2016.10.002. Epub 2016 Oct 13.

Abstract

PURPOSE

To evaluate the outcomes of pneumatic displacement of submacular hemorrhage secondary to choroidal neovascular membrane (CNV) ( = 9) and retinal arterial macroaneurysm (RAM) ( = 3).

METHODS

This is a retrospective case series study of 12 eyes from 12 patients in Aberdeen Royal Infirmary, Aberdeen, UK. The mean duration of visual loss was 10.8 ± 4.11 days. All cases received intravitreal injection of expansile gas within 24 h of presentation (C3F8 in 11 cases and SF6 in one case) and postured face down for five days. Anterior chamber paracentesis was done right after gas injection. Intravitreal anti-VEGF was injected at the same time in cases with CNV. Further anti-VEGF injections were done in CNV cases as needed afterwards. Cases were followed up for 6 months.

RESULTS

The submacular hemorrhage was successfully displaced from underneath the fovea in all but one case. The bleeding disappeared totally in 44% of cases and was inferiorly displaced in 56%. VA improvement at 6 months was statistically significantly higher than baseline VA. All cases but 2 (one because of subfoveal fibrosis and one because of late presentation) experienced improved VA. The mean VA improved from 1.37 ± 0.18 logMAR at baseline to 0.83 ± 0.26 logMAR at 6 months. No complication related to the procedure was reported.

CONCLUSION

Pneumatic displacement of submacular hemorrhage appears to be a safe and effective technique to treat the condition. It is an easy procedure that can be done in outpatient setting. Further studies are needed to validate our results.

摘要

目的

评估继发于脉络膜新生血管膜(CNV)(n = 9)和视网膜动脉大动脉瘤(RAM)(n = 3)的黄斑下出血进行气体置换的效果。

方法

这是一项对英国阿伯丁皇家医院12例患者的12只眼进行的回顾性病例系列研究。平均视力丧失持续时间为10.8 ± 4.11天。所有病例在就诊后24小时内接受玻璃体内注射膨胀性气体(11例注射C3F8,1例注射SF6),并面朝下体位保持5天。气体注射后立即进行前房穿刺。CNV病例同时注射玻璃体内抗VEGF药物。之后根据需要对CNV病例进一步注射抗VEGF药物。对病例进行6个月的随访。

结果

除1例病例外,其余所有病例的黄斑下出血均成功从黄斑中心凹下方移位。44%的病例出血完全消失,56%的病例出血向下移位。6个月时视力(VA)改善在统计学上显著高于基线视力。除2例(1例因黄斑中心凹下纤维化,1例因就诊较晚)外,所有病例的视力均有改善。平均视力从基线时的1.37 ± 0.18 logMAR提高到6个月时的0.83 ± 0.26 logMAR。未报告与该操作相关的并发症。

结论

黄斑下出血的气体置换似乎是一种治疗该疾病的安全有效的技术。这是一种简单的操作,可以在门诊进行。需要进一步研究来验证我们的结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/791c/5161816/57b2b9c3b915/gr1.jpg

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