Tang Calyn, Hoo Pearl Ching-Xin, Tan Loh Teng-Hern, Pusparajah Priyia, Khan Tahir Mehmood, Lee Learn-Han, Goh Bey-Hing, Chan Kok-Gan
Biomedical Research Laboratory, Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia Bandar Sunway, Malaysia.
Novel Bacteria and Drug Discovery Research Group, School of Pharmacy, Monash University Malaysia Bandar Sunway, Malaysia.
Front Pharmacol. 2016 Dec 7;7:474. doi: 10.3389/fphar.2016.00474. eCollection 2016.
(enoki, velvet shank, golden needle mushroom or winter mushroom), one of the main edible mushrooms on the market, has long been recognized for its nutritional value and delicious taste. In recent decades, research has expanded beyond detailing its nutritional composition and delved into the biological activities and potential health benefits of its constituents. Many bioactive constituents from a range of families have been isolated from different parts of the mushroom, including carbohydrates, protein, lipids, glycoproteins, phenols, and sesquiterpenes. These compounds have been demonstrated to exhibit various biological activities, such as antitumour and anticancer activities, anti-atherosclerotic and thrombosis inhibition activity, antihypertensive and cholesterol lowering effects, anti-aging and antioxidant properties, ability to aid with restoring memory and overcoming learning deficits, anti-inflammatory, immunomodulatory, anti-bacterial, ribosome inactivation and melanosis inhibition. This review aims to consolidate the information concerning the phytochemistry and biological activities of various compounds isolated from to demonstrate that this mushroom is not only a great source of nutrients but also possesses tremendous potential in pharmaceutical drug development.
金针菇(金针菇、金针菇、金针菇或冬菇)是市场上主要的食用菌之一,长期以来因其营养价值和美味口感而受到认可。近几十年来,研究范围已从详细描述其营养成分扩展到深入研究其成分的生物活性和潜在健康益处。已从蘑菇的不同部位分离出一系列家族的许多生物活性成分,包括碳水化合物、蛋白质、脂质、糖蛋白、酚类和倍半萜类。这些化合物已被证明具有多种生物活性,如抗肿瘤和抗癌活性、抗动脉粥样硬化和血栓形成抑制活性、降血压和降胆固醇作用、抗衰老和抗氧化特性、有助于恢复记忆和克服学习缺陷的能力、抗炎、免疫调节、抗菌、核糖体失活和抑制黑色素沉着。本综述旨在整合从[具体名称未给出]中分离出的各种化合物的植物化学和生物活性信息,以证明这种蘑菇不仅是一种优质的营养来源,而且在药物开发方面具有巨大潜力。