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在一例稳定期白癜风患者中使用新型负压表皮采集系统进行自体表皮移植

Autologous Epidermal Grafting Using a Novel Negative Pressure Epidermal Harvesting System in a Case of Stable Vitiligo.

作者信息

Krishna Aarthi, Thirunavukkarasu Vanathi, Navaneetha Krishnan Paru Priyadarshini, Danasekaran Nithya Gayathri Devi, Rajendrabose Ratnavel

机构信息

Department of Cosmetology, Government Stanley Medical College and Hospital.

出版信息

Cureus. 2016 Nov 15;8(11):e881. doi: 10.7759/cureus.881.

DOI:10.7759/cureus.881
PMID:28003945
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5158311/
Abstract

Vitiligo is a common pigmentary disorder of the skin with a great amount of social stigma attached to it. Though various medical modalities are available for the treatment of stable vitiligo, surgical modality remains the treatment of choice for stable and localized vitiligo. The surgical options range from simple punch grafting to the recent epidermal harvesting methods using a negative pressure unit. Although successful use of multiple methods of epidermal grafting has been reported, most of them are cumbersome and time-consuming. The new automated epidermal harvesting system now commercially available involves a tool that applies both heat and suction concurrently to normal skin to induce epidermal micrografts. Hence it serves as a safe, quick and cost-effective method without anesthesia, with a very minimal downtime for healing and requires an optimal expertise. The duration of repigmentation seems to be faster and more uniform compared to other procedures. We would like to share our experience with the negative pressure epidermal harvesting method in a patient with stable vitiligo.

摘要

白癜风是一种常见的皮肤色素沉着紊乱疾病,常伴有巨大的社会污名。尽管有多种医学方法可用于治疗稳定期白癜风,但手术方法仍是稳定期局限性白癜风的首选治疗方法。手术选择范围从简单的钻孔移植到最近使用负压装置的表皮采集方法。虽然已有多种表皮移植方法成功应用的报道,但大多数方法都繁琐且耗时。目前市面上的新型自动表皮采集系统包含一种工具,可同时对正常皮肤施加热量和吸力以诱导表皮微移植。因此,它是一种安全、快速且经济高效的方法,无需麻醉,愈合后的停工时间极短,且需要最佳的专业技术。与其他手术相比,色素再生的持续时间似乎更快且更均匀。我们希望分享我们在一位稳定期白癜风患者中使用负压表皮采集方法的经验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/781a28e1e0e5/cureus-0008-00000000881-i12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/434a7a26f93a/cureus-0008-00000000881-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/428318994e86/cureus-0008-00000000881-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/34d9f9117d15/cureus-0008-00000000881-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/c39790f498e9/cureus-0008-00000000881-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/1bd008d21028/cureus-0008-00000000881-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/cfd869cbfe54/cureus-0008-00000000881-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/d515e8ff4127/cureus-0008-00000000881-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/eca6dcbddc7a/cureus-0008-00000000881-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/3b19bf2dfe06/cureus-0008-00000000881-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/57b900781c81/cureus-0008-00000000881-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/3066b7c41c17/cureus-0008-00000000881-i11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/781a28e1e0e5/cureus-0008-00000000881-i12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/434a7a26f93a/cureus-0008-00000000881-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/428318994e86/cureus-0008-00000000881-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/34d9f9117d15/cureus-0008-00000000881-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/c39790f498e9/cureus-0008-00000000881-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/1bd008d21028/cureus-0008-00000000881-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/cfd869cbfe54/cureus-0008-00000000881-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/d515e8ff4127/cureus-0008-00000000881-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/eca6dcbddc7a/cureus-0008-00000000881-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/3b19bf2dfe06/cureus-0008-00000000881-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/57b900781c81/cureus-0008-00000000881-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/3066b7c41c17/cureus-0008-00000000881-i11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/feeb/5158311/781a28e1e0e5/cureus-0008-00000000881-i12.jpg

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本文引用的文献

1
Epidermal micrografts produced via an automated and minimally invasive tool form at the dermal/epidermal junction and contain proliferative cells that secrete wound healing growth factors.通过自动化微创工具产生的表皮微移植体在真皮/表皮交界处形成,并含有分泌伤口愈合生长因子的增殖细胞。
Adv Skin Wound Care. 2015 Sep;28(9):397-405. doi: 10.1097/01.ASW.0000470024.81711.b8.
2
Study of clinical, biochemical and immunological factors determining stability of disease in patients with generalized vitiligo undergoing melanocyte transplantation.研究影响泛发性白癜风患者黑素细胞移植后疾病稳定性的临床、生化和免疫学因素。
Br J Dermatol. 2012 Jun;166(6):1230-6. doi: 10.1111/j.1365-2133.2012.10886.x.
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Tissue grafts in vitiligo surgery - past, present, and future.
白癜风手术中的组织移植——过去、现在与未来。
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Standard guidelines of care for vitiligo surgery.白癜风手术的标准护理指南。
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Surgical treatment of vitiligo: why, when and how.白癜风的外科治疗:原因、时机与方法
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Dermatology Life Quality Index (DLQI)--a simple practical measure for routine clinical use.皮肤病生活质量指数(DLQI)——一种用于日常临床的简单实用测量方法。
Clin Exp Dermatol. 1994 May;19(3):210-6. doi: 10.1111/j.1365-2230.1994.tb01167.x.
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Melanocyte autologous grafting for treatment of leukoderma.黑素细胞自体移植治疗白癜风。
J Am Acad Dermatol. 1985 Dec;13(6):968-74. doi: 10.1016/s0190-9622(85)70247-2.