儿童产前和产后接触宠物、血压与高血压：东北七城市研究
Prenatal and postnatal exposure to pet ownership, blood pressure, and hypertension in children: the Seven Northeastern Cities study.
作者信息
Xu Shu-Li, Trevathan Edwin, Qian Zhengmin, Vivian Elaina, Yang Bo-Yi, Hu Li-Wen, Zeng Xiao-Wen, Li Meng, Zhou Yang, Qin Xiao-Di, Bao Wen-Wen, Yuan Ping, Zhang Ya-Zhi, Wang Jia, Zhang Chuan, Tian Yan-Peng, Nian Min, Xiao Xiang, Dong Guang-Hui
机构信息
aGuangzhou Key Laboratory of Environmental Pollution and Health Risk Assessment, Department of Preventive Medicine, School of Public Health, Sun Yat-sen University, Guangzhou, ChinabDepartments of Pediatrics, Division of Pediatric and Neurology, and Vanderbilt Institute for Global Health, Vanderbilt University School of Medicine, Nashville, TennesseecDepartment of Epidemiology, College for Public Health and Social Justice, Saint Louis University, Saint Louis, Missouri, USA.
出版信息
J Hypertens. 2017 Feb;35(2):259-265. doi: 10.1097/HJH.0000000000001166.
OBJECTIVE
There is little information about how exposure to pets impacts blood pressure (BP) in children. The objective of the present study was to investigate the association between pet exposure and BP in children.
METHODS
A total of 9354 children, aged 5-17 years, from 24 elementary schools and 24 middle schools in the Seven Northeastern Cities were evaluated during 2012-2013. BP measurements were taken using a mercury sphygmomanometer. Hypertension in children was defined as having an average DBP or SBP in the 95th percentile or higher for the child's sex, age, and height.
RESULTS
Overall, 2127 of the 9354 participants (22.7%) had current exposures to pets, with 989 of all participants having dogs (10.6%). Pet exposure was negatively associated with hypertension and BP in men and women. Keeping dogs in the home was related to a significantly lower prevalence of hypertension in men [adjusted odds ratio (aOR) = 0.68; 95% confidence interval (CI): 0.49-0.94] and women (aOR = 0.66; 95% CI: 0.48-0.90). When the analysis was stratified by sex, in-utero exposure to pets was negatively associated with hypertension in men (aOR = 0.66; 95% CI: 0.45-0.97), and the associations with lower BP strengthened with higher levels of current pet exposure. As for BP, the associations between pet exposure and DBP were detected more in women; estimated decreases in mean DBP was 1.10 mmHg (95% CI: -1.75 to -0.45) for current pet exposure.
CONCLUSION
Pet ownership reduces the odds of hypertension and elevated BP in children.
目的
关于接触宠物如何影响儿童血压（BP）的信息很少。本研究的目的是调查儿童接触宠物与血压之间的关联。
方法
2012 - 2013年期间，对来自东北七城市24所小学和24所中学的9354名5 - 17岁儿童进行了评估。使用汞柱式血压计测量血压。儿童高血压定义为其舒张压（DBP）或收缩压（SBP）平均值处于其性别、年龄和身高对应的第95百分位数或更高。
结果
总体而言，9354名参与者中有2127名（22.7%）目前接触宠物，其中989名（10.6%）养犬。接触宠物与男性和女性的高血压及血压呈负相关。在家中养犬与男性[调整优势比（aOR）= 0.68；95%置信区间（CI）：0.49 - 0.94]和女性（aOR = 0.66；95% CI：0.48 - 0.90）高血压患病率显著降低有关。按性别分层分析时，男性子宫内接触宠物与高血压呈负相关（aOR = 0.66；95% CI：0.45 - 0.97），且当前宠物接触水平越高与较低血压的关联越强。至于血压方面，则在女性中更多检测到宠物接触与舒张压之间的关联；当前宠物接触使平均舒张压估计降低1.10 mmHg（95% CI： - 1.75至 - 0.45）。
结论
养宠物可降低儿童患高血压和血压升高的几率。
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