Carr David B, Barco Peggy P, Babulal Ganesh M, Stout Sarah H, Johnson Anne M, Xiong Chengjie, Morris John C, Roe Catherine M
Division of Geriatrics and Nutritional Science, Division of Neurorehabilitation, Washington University in St. Louis, The Rehabilitation Institute of St. Louis (TRISL), Parc Provence, St. Louis, MO, United States of America.
Program in Occupational Therapy, Washington University in St. Louis, St. Louis, MO, United States of America.
PLoS One. 2016 Dec 22;11(12):e0167751. doi: 10.1371/journal.pone.0167751. eCollection 2016.
To examine the relationship between key functional impairments, co-morbid conditions and driving performance in a sample of cognitively normal older adults.
Prospective observational study.
The Knight Alzheimer's Disease Research Center, Washington University at St. Louis.
Individuals with normal cognition, 64.9 to 88.2 years old (N = 129), with a valid driver's license, who were currently driving at least once per week, and who had participated in longitudinal studies at the Knight Alzheimer's Disease Research Center.
Static visual acuity, contrast sensitivity, physical frailty measures, motor skills, total medical conditions, and the modified Washington University Road Test.
When controlling for age, race, gender, APOE, and education the total number of medical conditions was unassociated with both road test scores (pass vs. marginal + fail) and the total driver error count. There were marginal associations of our measure of physical frailty (p = 0.06) and contrast sensitivity score (p = 0.06) with total driving error count.
Future research that focuses on older adults and driving should consider adopting measures of physical frailty and contrast sensitivity, especially in samples that may have a propensity for disease impacting visual and/or physical function (e.g. osteoarthritis, Parkinson's, eye disorders, advanced age >80 years, etc.).
在认知正常的老年人样本中,研究关键功能障碍、共病情况与驾驶性能之间的关系。
前瞻性观察性研究。
圣路易斯华盛顿大学奈特阿尔茨海默病研究中心。
认知正常、年龄在64.9至88.2岁之间(N = 129)、持有有效驾照、目前每周至少驾驶一次且曾参与奈特阿尔茨海默病研究中心纵向研究的个体。
静态视力、对比敏感度、身体虚弱指标、运动技能、总体医疗状况以及改良的华盛顿大学道路测试。
在控制年龄、种族、性别、载脂蛋白E和教育程度后,总体医疗状况与道路测试分数(通过与边缘 + 未通过)及总驾驶错误计数均无关联。我们的身体虚弱指标(p = 0.06)和对比敏感度分数(p = 0.06)与总驾驶错误计数存在边缘关联。
未来针对老年人与驾驶的研究应考虑采用身体虚弱和对比敏感度的测量方法,尤其是在可能倾向于患有影响视觉和/或身体功能疾病的样本中(例如骨关节炎、帕金森病、眼部疾病、年龄 > 80岁等)。