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与保守治疗相比,多发伤情况下胸廓骨固定术的效果:一项系统评价

Effects of osteosynthesis of the bony thorax in the context of polytrauma compared to conservative treatment: a systematic review.

作者信息

Dahms Karolina, Volmerig Jan, Dormann Julia, Steinfeld Eva, Ansems Kelly, Janka Heidrun, Metzendorf Maria-Inti, Benstoem Carina

机构信息

Department of Intensive Care Medicine and Intermediate Care Medical Faculty, RWTH Aachen University, Pauwelsstr. 30, D-52074, Aachen, Germany.

Clinic for Thoracic Surgery, Evang. Kliniken Essen-Mitte, University of Duisburg-Essen, Essen, Germany.

出版信息

Eur J Trauma Emerg Surg. 2025 Jan 24;51(1):45. doi: 10.1007/s00068-024-02760-z.

Abstract

PURPOSE

Osteosynthesis seems to have effects regarding clinical outcomes in trauma patients. However, current knowledge on chest wall osteosynthesis in polytrauma patients is insufficient, leaving its potential unanswered. Therefore, the objective of this systematic review is to assess the safety and effects of chest wall osteosynthesis compared to conservative treatment on clinical outcomes in adult polytrauma patients.

METHODS

We searched PubMed to identify completed and ongoing studies from inception of each database to May, 2022. We included systematic reviews including RCTs comparing chest wall osteosynthesis to conservative treatment in adult polytrauma patients.

RESULTS

We included one RCT with 50 patients (n = 25, n = 25, median age 37.4 years, 82% male). We found that surgical rib fixation makes little or no difference to in-hospital mortality compared to conservative treatment (RR 2.00, 95% CI 0.40 to 9.95; RD 80 more per 1,000, 95% CI 48 fewer to 716 more; 1 study, 50 participants, low quality of evidence). We found that surgical rib fixation makes little or no difference to the need for mechanical ventilation compared to conservative treatment (RR 0.90, 95% CI -0.66 to 1.23; RD 80 fewer per 1,000, 95% CI 272 fewer to 184 more; 1 study, 50 participants, low certainty of evidence).

CONCLUSION

There is limited evidence regarding chest wall osteosynthesis compared to conservative treatment in polytrauma patients. One RCT shows no effect of surgical rib fixation compared to conservative treatment regarding mortality and clinical status, but a potential benefit regarding ICU length of stay.

摘要

目的

骨固定术似乎对创伤患者的临床结局有影响。然而,目前关于多发伤患者胸壁骨固定术的知识不足,其潜力尚未得到解答。因此,本系统评价的目的是评估与保守治疗相比,胸壁骨固定术对成年多发伤患者临床结局的安全性和效果。

方法

我们检索了PubMed,以识别从每个数据库建立之初到2022年5月的已完成和正在进行的研究。我们纳入了系统评价,包括比较成年多发伤患者胸壁骨固定术与保守治疗的随机对照试验。

结果

我们纳入了一项有50名患者的随机对照试验(n = 25,n = 25,中位年龄37.4岁,82%为男性)。我们发现,与保守治疗相比,手术肋骨固定对院内死亡率几乎没有影响(风险比2.00,95%置信区间0.40至9.95;每1000人多80例,95%置信区间少48例至多716例;1项研究,50名参与者,证据质量低)。我们发现,与保守治疗相比,手术肋骨固定对机械通气需求几乎没有影响(风险比0.90,95%置信区间-0.66至1.23;每1000人少80例,95%置信区间少272例至多184例;1项研究,50名参与者,证据确定性低)。

结论

与多发伤患者的保守治疗相比,关于胸壁骨固定术的证据有限。一项随机对照试验表明,与保守治疗相比,手术肋骨固定在死亡率和临床状况方面没有效果,但在重症监护病房住院时间方面可能有好处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0faa/11761492/0d386620bf1d/68_2024_2760_Fig1_HTML.jpg

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