Gong J, Kelly P, Wang C
Poultry Institute, Chinese Academy of Agricultural Sciences, Yangzhou, Jiangsu, China.
Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu, China.
Zoonoses Public Health. 2017 Jun;64(4):239-251. doi: 10.1111/zph.12328. Epub 2016 Dec 23.
Salmonella enterica serovar Indiana, first described in 1955, is generally regarded as having a low frequency worldwide with outbreaks of gastroenteritis and abortions described in North America and Europe. In China, S. Indiana was first reported in 1984 and in the subsequent 71 surveys in 35 cities/municipalities from 18 provinces, 70% of which were after 2012, S. Indiana has been shown to have become widely prevalent in people, animals, food and the environment around abattoirs and meat processing facilities. The organism is now one of the most common serovars found in livestock and raw meat in China with S. Indiana isolates having high levels of drug resistance, especially against tetracyclines, quinolones, folate pathway inhibitors, phenicols, penicillins, monobactams and nitrofurans. Further, S. Indiana isolates that are concurrently resistant to ciprofloxacin and ceftriaxone/cefotaxime have emerged. Studies have suggested the high levels of multidrug resistance of S. Indiana might be associated with the presence of class 1 integrons and plasmids. Unfortunately, information on the high prevalence of S. Indiana and its extensive drug resistance in China has largely escaped international recognition as it largely appears in local reports written in Chinese. To address this situation, we reviewed all the available local Chinese and international publications on the organism in China and report our findings in this review.
肠炎沙门氏菌印第安纳血清型于1955年首次被描述，在全球范围内通常被认为出现频率较低，北美和欧洲曾有过肠胃炎和流产暴发的报道。在中国，1984年首次报告发现印第安纳沙门氏菌，在随后对来自18个省份的35个市/直辖市进行的71次调查中（其中70%是在2012年之后），印第安纳沙门氏菌已被证明在人、动物、食品以及屠宰场和肉类加工设施周边环境中广泛流行。该菌现已成为中国家畜和生肉中最常见的血清型之一，印第安纳沙门氏菌分离株具有很高的耐药性，尤其是对四环素、喹诺酮类、叶酸途径抑制剂、氯霉素、青霉素、单环β-内酰胺类和硝基呋喃类药物。此外，同时对环丙沙星和头孢曲松/头孢噻肟耐药的印第安纳沙门氏菌分离株也已出现。研究表明，印第安纳沙门氏菌的高度多重耐药性可能与1类整合子和质粒的存在有关。不幸的是，中国印第安纳沙门氏菌的高流行率及其广泛的耐药性信息在很大程度上未得到国际认可，因为这些信息大多出现在中文的地方报告中。为了解决这一情况，我们查阅了所有关于中国该菌的中文和英文本地及国际出版物，并在本综述中报告我们的研究结果。
