Adachi K, Aoki T
Department of Dermatology, Habikino Hospital of Osaka Prefecture, Japan.
Acta Derm Venereol Suppl (Stockh). 1989;144:83-7. doi: 10.2340/000155551448387.
Of 45 patients with atopic dermatitis skin-tested with their own sweat, 43 showed positive immediate-type skin reactions to titres between 1 and 256. Of 22 non-atopic patients 18 showed negative reactions. Skin reactivity of the atopic patients to the sweat and house dust did not run parallel. Radioallergosorbent test (RAST) using the sweat collected from a healthy subject detected IgE antibody in 24 atopic patients with a score from 0.5 to 3.5, whereas all the control subjects showed the score 0. This IgE antibody to sweat did not cross-react with the mite extract (Dermatophagoides farinae) or Staphylococcus aureus. These results indicate that atopic patients have specific IgE antibody to sweat.
45名特应性皮炎患者用自身汗液进行皮肤试验，其中43人对1至256的滴度显示出阳性速发型皮肤反应。22名非特应性患者中，18人显示阴性反应。特应性患者对汗液和屋尘的皮肤反应性不平行。使用从健康受试者收集的汗液进行的放射变应原吸附试验（RAST）在24名特应性患者中检测到IgE抗体，评分为0.5至3.5，而所有对照受试者的评分为0。这种针对汗液的IgE抗体与螨提取物（粉尘螨）或金黄色葡萄球菌无交叉反应。这些结果表明，特应性患者对汗液有特异性IgE抗体。
