Akeson J, Boström P A, Gustafson C, Rosberg B
Department of Anaesthesiology and Intensive Care Medicine, University of Lund, Malmö General Hospital, Sweden.
Acta Anaesthesiol Scand. 1989 Aug;33(6):435-8. doi: 10.1111/j.1399-6576.1989.tb02941.x.
Skeletal muscle trauma and myocardial infarction both increase the serum values of the creatine kinase isoenzyme MB (CK-MB) which may render the diagnosis of perioperative myocardial infarction in major orthopaedic surgery more difficult. The significance of postoperative changes in CK-MB was studied in 30 patients subjected to total hip replacement (THR), and the results were compared to CK-MB in 30 nonsurgical patients with acute myocardial infarction (AMI). AMI patients had significantly higher serum CK-MB values at 24 h than THR patients. However, the highest value after THR exceeded the lowest value in AMI. The results suggest that skeletal muscle release of CK-MB after THR is slight. CK-MB thus also seems useful in the diagnosis of AMI in postoperative patients.
骨骼肌创伤和心肌梗死都会使肌酸激酶同工酶MB（CK-MB）的血清值升高，这可能会使大型骨科手术中围手术期心肌梗死的诊断更加困难。对30例行全髋关节置换术（THR）的患者术后CK-MB变化的意义进行了研究，并将结果与30例急性心肌梗死（AMI）非手术患者的CK-MB进行了比较。AMI患者在24小时时的血清CK-MB值明显高于THR患者。然而，THR后的最高值超过了AMI中的最低值。结果表明，THR后骨骼肌释放的CK-MB很少。因此，CK-MB似乎也有助于术后患者AMI的诊断。
