Adaptive Optics Imaging in Retinal Vasculitis.

PURPOSE

To study the sheathing of retinal vasculitis in various systemic autoimmune diseases using adaptive optics imaging (AOI).

METHODS

Prospective, observational case series with six patients: Behçet disease (n = 1); systemic lupus erythematosus (n = 1); idiopathic retinal vasculitis (n = 2); granulomatosis with polyangiitis (n = 1); and Takayasu aorta arteritis (n = 1). Fundus photograph (FP), fundus fluorescein angiography (FFA) were done in all cases at presentation. Using the Image J software, perivascular sheathing and wall-to-wall diameter of the vessel involved were measured on AOI at time of presentation and on follow-up.

RESULTS

AOI was able to pick the pipe-stem sheathing in SLE and IRV(I) and parallel sheathing in rest, which correlated with FP and FFA. Moreover, the decrease and a complete resolution in the sheathing were also noted by AOI on follow-up.

CONCLUSIONS

AOI can be used as an additional investigative tool for diagnosis and to monitor the disease course during the treatment.