Extracellular vesicles as therapeutic carriers of microRNAs for cholangiocarcinoma.
作者信息
Gradilone Sergio A
机构信息
The Hormel Institute, University of Minnesota, Austin, MN.
出版信息
Hepatology. 2017 Feb;65(2):404-406. doi: 10.1002/hep.28925. Epub 2016 Dec 24.
Abstract
摘要
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本文引用的文献
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Extracellular vesicles carry microRNA-195 to intrahepatic cholangiocarcinoma and improve survival in a rat model.细胞外囊泡将微小RNA-195携带至肝内胆管癌，并改善大鼠模型的生存率。
Hepatology. 2017 Feb;65(2):501-514. doi: 10.1002/hep.28735. Epub 2016 Aug 29.
2
Extracellular Vesicles: Satellites of Information Transfer in Cancer and Stem Cell Biology.细胞外囊泡：癌症与干细胞生物学中的信息传递卫星
Dev Cell. 2016 May 23;37(4):301-309. doi: 10.1016/j.devcel.2016.04.019.
3
Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA).专家共识文件：胆管癌：来自欧洲胆管癌研究网络（ENS-CCA）的当前知识和未来展望共识声明。
Nat Rev Gastroenterol Hepatol. 2016 May;13(5):261-80. doi: 10.1038/nrgastro.2016.51. Epub 2016 Apr 20.
4
Exosomes in liver pathology.肝脏病理学中的外泌体
J Hepatol. 2016 Jul;65(1):213-221. doi: 10.1016/j.jhep.2016.03.004. Epub 2016 Mar 14.
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Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.胆管癌外泌体的蛋白质组学分析：致癌蛋白转移在癌症进展中的潜在作用。
Biochim Biophys Acta. 2015 Sep;1852(9):1989-99. doi: 10.1016/j.bbadis.2015.06.024. Epub 2015 Jul 3.
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Hepatic stellate cell and monocyte interaction contributes to poor prognosis in hepatocellular carcinoma.肝星状细胞与单核细胞相互作用导致肝细胞癌预后不良。
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Tumour cell-derived extracellular vesicles interact with mesenchymal stem cells to modulate the microenvironment and enhance cholangiocarcinoma growth.肿瘤细胞衍生的细胞外囊泡与间充质干细胞相互作用，调节微环境并增强胆管癌生长。
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Human bile contains microRNA-laden extracellular vesicles that can be used for cholangiocarcinoma diagnosis.人胆汁中含有富含 microRNA 的细胞外囊泡，可用于胆管癌的诊断。
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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.外泌体介导的mRNA和微小RNA转移是细胞间基因交换的一种新机制。
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