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Neuropsychopharmacology. 2016 Feb;41(3):877-85. doi: 10.1038/npp.2015.214. Epub 2015 Jul 16.
2
Examining the relationship between cue-induced craving and actual smoking.研究线索诱导的渴望与实际吸烟之间的关系。
Exp Clin Psychopharmacol. 2015 Apr;23(2):90-6. doi: 10.1037/a0038826. Epub 2015 Mar 2.
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Role of corticostriatal circuits in context-induced reinstatement of drug seeking.皮质纹状体回路在情境诱导的药物寻求恢复中的作用。
Brain Res. 2015 Dec 2;1628(Pt A):219-32. doi: 10.1016/j.brainres.2014.09.004. Epub 2014 Sep 6.
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Nicotine Tob Res. 2013 Dec;15(12):2081-7. doi: 10.1093/ntr/ntt104. Epub 2013 Jul 19.
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Developing and validating a human laboratory model to screen medications for smoking cessation.开发和验证一种人类实验室模型,以筛选戒烟药物。
Nicotine Tob Res. 2012 Nov;14(11):1362-71. doi: 10.1093/ntr/nts090. Epub 2012 Apr 6.
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Relapse dynamics during smoking cessation: recurrent abstinence violation effects and lapse-relapse progression.戒烟期间的复吸动态:复发的戒断违反效应和复吸-复发进展。
J Abnorm Psychol. 2012 Feb;121(1):187-97. doi: 10.1037/a0024451. Epub 2011 Jul 25.
7
Stress decreases the ability to resist smoking and potentiates smoking intensity and reward.压力会降低抵抗吸烟的能力,并增强吸烟的强度和快感。
J Psychopharmacol. 2011 Apr;25(4):490-502. doi: 10.1177/0269881110376694. Epub 2010 Sep 3.
8
Bringing the real world into the laboratory: personal smoking and nonsmoking environments.将真实世界带入实验室:个人吸烟和非吸烟环境。
Drug Alcohol Depend. 2010 Sep 1;111(1-2):58-63. doi: 10.1016/j.drugalcdep.2010.03.017. Epub 2010 May 26.
9
Relapse to drug seeking following prolonged abstinence: the role of environmental stimuli.长期禁欲后复吸寻求药物行为:环境刺激的作用
Drug Discov Today Dis Models. 2008 Winter;5(4):251-258. doi: 10.1016/j.ddmod.2009.03.001.
10
Proximal versus distal cues to smoke: the effects of environments on smokers' cue-reactivity.近端与远端吸烟线索:环境对吸烟者线索反应性的影响。
Exp Clin Psychopharmacol. 2008 Jun;16(3):207-14. doi: 10.1037/1064-1297.16.3.207.

吸烟环境线索会降低通过延迟吸烟任务所衡量的抵抗吸烟的能力。

Smoking environment cues reduce ability to resist smoking as measured by a delay to smoking task.

作者信息

Stevenson Jennifer G, Oliver Jason A, Hallyburton Matthew B, Sweitzer Maggie M, Conklin Cynthia A, McClernon F Joseph

机构信息

Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27705, United States.

Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27705, United States.

出版信息

Addict Behav. 2017 Apr;67:49-52. doi: 10.1016/j.addbeh.2016.12.007. Epub 2016 Dec 18.

DOI:10.1016/j.addbeh.2016.12.007
PMID:28012965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5478924/
Abstract

INTRODUCTION

Environments associated with smoking may promote lapse and relapse in smokers attempting to quit. Here we examined the effects of exposure to visual smoking environment cues on smoking urge and the ability to resist smoking, as measured with a delay-to-smoking task in which monetary contingencies are provided for resisting smoking.

METHODS

Adult daily smokers (n=22) completed two experimental sessions, each following 6h smoking abstinence. Sessions differed only in the type of cue participants were exposed to (smoking environments vs. nonsmoking environments). Participants completed subjective ratings of smoking urge, withdrawal and other reactions (i.e. craving, affect). Behavioral outcomes on the delay-to-smoking task included latency to first cigarette, number of cigarettes smoked and average number of puffs per cigarette.

RESULTS

Across cue exposure sessions, 64% of participants initiated smoking (no effect of condition was observed). However, exposure to smoking environments as compared to the nonsmoking environments resulted in greater craving, faster initiation of smoking, and more smoked cigarettes. Greater craving was associated with a shorter time to initiate smoking, but this effect did not differ across sessions. In contrast, withdrawal was more strongly associated with number of cigarettes smoked during smoking environment sessions.

CONCLUSION

Together, these results suggest smoking environments increase smoking urge and promote smoking behavior. Further research is necessary to examine the specific and interactive effects of smoking-related environments on real-world smoking lapse and relapse.

摘要

引言

与吸烟相关的环境可能会促使试图戒烟的吸烟者出现复吸和复发。在此,我们通过一项延迟吸烟任务来研究暴露于视觉吸烟环境线索对吸烟冲动及抵抗吸烟能力的影响,该任务为抵抗吸烟提供金钱奖励。

方法

成年每日吸烟者(n = 22)完成两个实验环节,每个环节前均有6小时的戒烟期。各环节的差异仅在于参与者所暴露的线索类型(吸烟环境与非吸烟环境)。参与者完成对吸烟冲动、戒断反应及其他反应(即渴望、情绪)的主观评分。延迟吸烟任务的行为结果包括首次吸烟的潜伏期、吸烟数量及每支烟的平均吸数。

结果

在不同线索暴露环节中,64%的参与者开始吸烟(未观察到条件效应)。然而,与非吸烟环境相比,暴露于吸烟环境会导致更强烈的渴望、更快开始吸烟以及吸更多的烟。更强烈的渴望与更短的开始吸烟时间相关,但这种效应在各环节中并无差异。相比之下,在吸烟环境环节中,戒断反应与吸烟数量的关联更为紧密。

结论

这些结果共同表明,吸烟环境会增加吸烟冲动并促进吸烟行为。有必要进行进一步研究,以考察与吸烟相关的环境对现实世界中吸烟复吸和复发的具体及交互作用。