Conklin Cynthia A, Robin Nathalie, Perkins Kenneth A, Salkeld Ronald P, McClernon F Joseph
University of Pittsburgh, Pittsburg, PA, USA.
Exp Clin Psychopharmacol. 2008 Jun;16(3):207-14. doi: 10.1037/1064-1297.16.3.207.
Smokers are highly reactive to smoking-related cues that are directly linked, or most proximal, to actual smoking behavior (e.g., lit cigarettes). However, over the course of smoking, proximal cues may not be the only stimuli to become strongly associated with smoking. Distal cues, such as the environments in which smoking occurs (e.g., bar) might also gain associative properties and come to evoke robust reactivity from smokers. To test this, a pilot study was first conducted to develop standard pictorial stimuli of smoking and nonsmoking environments, all of which were completely devoid of proximal smoking cues. A comparison set of smoking and nonsmoking proximal cues was then created. Using the 12 total pictorial cues developed, 62 adult smokers participated in a cue-reactivity study during which they viewed and rated pictorial smoking and nonsmoking environment and proximal cues. Results demonstrate that, similar to proximal cues, environments associated with smoking can alone function as stimuli capable of evoking strong subjective reactivity from smokers. This work supports a broader conceptualization of drug-related cues in cue-based research and treatment development that includes proximal and distal cues as distinct categories. (PsycINFO Database Record (c) 2008 APA, all rights reserved).
吸烟者对与吸烟相关的线索高度敏感,这些线索与实际吸烟行为直接相关,或者是最直接的(例如点燃的香烟)。然而,在吸烟过程中,直接线索可能不是唯一与吸烟紧密相关的刺激因素。间接线索,比如吸烟发生的环境(例如酒吧),也可能获得关联属性,并引发吸烟者强烈的反应。为了验证这一点,首先进行了一项初步研究,以开发吸烟和非吸烟环境的标准图片刺激物,所有这些刺激物都完全没有直接的吸烟线索。然后创建了一组吸烟和非吸烟直接线索的对照物。使用总共开发的12张图片线索,62名成年吸烟者参与了一项线索反应性研究,在此期间他们观看并对吸烟和非吸烟环境以及直接线索的图片进行评分。结果表明,与直接线索类似,与吸烟相关的环境本身就可以作为能够引发吸烟者强烈主观反应的刺激物。这项工作支持了在基于线索的研究和治疗开发中对与药物相关线索的更广泛概念化,其中包括将直接和间接线索作为不同类别。(PsycINFO数据库记录(c)2008美国心理学会,保留所有权利)