Theodoridis Charis, Grigoriadis Andreas, Menexes Georgios, Vouros Ioannis
Department of Dentoalveolar Surgery, Implant Surgery and Radiology, Faculty of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Department of Preventive Dentistry, Periodontology and Implant Biology, Faculty of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Clin Oral Investig. 2017 Mar;21(2):485-503. doi: 10.1007/s00784-016-2026-6. Epub 2016 Dec 24.
To investigate the outcomes of implant therapy in partially dentate patients treated for aggressive periodontitis (GAgP) in comparison to periodontally healthy (HP) and patients treated for chronic periodontitis (CP) utilizing radiographic and clinical parameters.
An electronic search of databases, supplemented by hand searching, was conducted to identify relevant clinical studies. Sequential screenings at the title, abstract and full-text levels were performed independently and in duplicate. A random effects meta-analysis was conducted and bias corrected bootstrap 95 % confidence intervals were estimated for group comparisons.
The search strategy revealed a total of 899 results. After title screening, abstract scanning, and full-text reading, seven articles fulfilled the inclusion criteria. The 3-year survival rate for CP and HP patients was 100 % while in GAgP subjects, the respective value was 97.98 %; this difference being statistically significant. The 3-year mean marginal bone loss (MBL) was 1.07 mm for the GAgP group, 0.47 mm for the CP group, and 0.69 mm for the HP group. A significant difference between the GAgP and CP groups was identified (p < 0.05). The weighted mean differences of MBL concerning the above groups were also calculated and examined for statistical significance in both 1 and 3 years.
The 3-year survival rate and peri-implant marginal bone loss was found statistically significantly lower in GAgP subjects (SR 97.98 % vs 100 %) in comparison to HP and CP individuals.
The outcome of implant therapy in terms of survival rate and marginal bone loss is considered very important for the clinician in decision making when placing implants in patients with a history of aggressive periodontitis.
利用影像学和临床参数，研究侵袭性牙周炎（GAgP）部分牙列缺损患者与牙周健康（HP）及慢性牙周炎（CP）患者种植治疗的效果。
通过电子检索数据库，并辅以手工检索，以识别相关临床研究。独立且重复地在标题、摘要和全文层面进行序贯筛选。进行随机效应荟萃分析，并估计组间比较的偏差校正自举95%置信区间。
检索策略共获得899条结果。经过标题筛选、摘要扫描和全文阅读，7篇文章符合纳入标准。CP和HP患者的3年生存率为100%，而GAgP患者的相应值为97.98%；这种差异具有统计学意义。GAgP组的3年平均边缘骨丢失（MBL）为1.07mm，CP组为0.47mm，HP组为0.69mm。GAgP组和CP组之间存在显著差异（p<0.05）。还计算了上述组间MBL的加权平均差异，并在1年和3年时检验其统计学意义。
与HP和CP个体相比，GAgP患者（SR 97.98% vs 100%）的3年生存率和种植体周围边缘骨丢失在统计学上显著更低。
对于有侵袭性牙周炎病史的患者，种植治疗在生存率和边缘骨丢失方面的结果对于临床医生在决定是否植入种植体时非常重要。
