对已知影响牛生产性能和健康的特定基因的综述
A Review of Selected Genes with Known Effects on Performance and Health of Cattle.
作者信息
Casas Eduardo, Kehrli Marcus E
机构信息
National Animal Disease Center, USDA, ARS , Ames, IA , USA.
出版信息
Front Vet Sci. 2016 Dec 15;3:113. doi: 10.3389/fvets.2016.00113. eCollection 2016.
Abstract
There are genetic conditions that influence production in dairy and beef cattle. The objective of this review was to describe relevant genetic conditions that have been associated with productivity and health in cattle. Genes or genomic regions that have been identified as a candidate for the condition will be included, and the genetic basis of the condition will be defined. Genes and genetic conditions included in this review are bovine leukocyte adhesion deficiency, deficiency of the uridine monophosphate synthase, bovine chronic interstitial nephritis, horn development, myostatin, complex vertebral malformation, leptin, osteopetrosis, apoptosis peptide activating factor 1, chondrodysplastic dwarfism, caseins, calpastatin, umbilical hernia, lactoglobulin, citrullinemia, cholesterol deficiency, prions, thyroglobulin, diacylglycerol acyltransferase, syndactyly, maple syrup urine disease, slick hair, Factor XI deficiency, and μ-Calpain. This review is not meant to be comprehensive, and relevant information is provided to ascertain genetic markers associated with the conditions.
摘要
存在一些影响奶牛和肉牛生产性能的遗传疾病。本综述的目的是描述与牛的生产性能和健康相关的遗传疾病。已被确定为该疾病候选基因的基因或基因组区域将被纳入，同时将明确该疾病的遗传基础。本综述中包括的基因和遗传疾病有牛白细胞黏附缺陷症、尿苷单磷酸合酶缺乏症、牛慢性间质性肾炎、角发育、肌肉生长抑制素、复杂脊椎畸形、瘦素、骨质石化症、凋亡肽激活因子1、软骨发育不良侏儒症、酪蛋白、钙蛋白酶抑制蛋白、脐疝、乳球蛋白、瓜氨酸血症、胆固醇缺乏症、朊病毒、甲状腺球蛋白、二酰基甘油酰基转移酶、并指畸形、枫糖尿症、光滑毛、因子XI缺乏症和μ-钙蛋白酶。本综述并非旨在全面涵盖，而是提供相关信息以确定与这些疾病相关的遗传标记。
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本文引用的文献
1
Identification of a nonsense mutation in APAF1 that is likely causal for a decrease in reproductive efficiency in Holstein dairy cattle.鉴定出APAF1中的一个无义突变，该突变可能是荷斯坦奶牛繁殖效率下降的原因。
J Dairy Sci. 2016 Aug;99(8):6693-6701. doi: 10.3168/jds.2015-10517. Epub 2016 Jun 8.
2
A transposable element insertion in APOB causes cholesterol deficiency in Holstein cattle.载脂蛋白B中的转座子插入导致荷斯坦奶牛胆固醇缺乏。
Anim Genet. 2016 Apr;47(2):253-7. doi: 10.1111/age.12410. Epub 2016 Jan 13.
3
Developmental progress and current status of the Animal QTLdb.动物数量性状基因座数据库的发展进程与现状
Nucleic Acids Res. 2016 Jan 4;44(D1):D827-33. doi: 10.1093/nar/gkv1233. Epub 2015 Nov 23.
4
The transmissible spongiform encephalopathies of livestock.家畜的传染性海绵状脑病
ILAR J. 2015;56(1):7-25. doi: 10.1093/ilar/ilv008.
5
Susceptibility loci revealed for bovine respiratory disease complex in pre-weaned holstein calves.揭示了断奶前荷斯坦犊牛牛呼吸道疾病综合征的易感基因座。
BMC Genomics. 2014 Dec 22;15(1):1164. doi: 10.1186/1471-2164-15-1164.
6
Functionally reciprocal mutations of the prolactin signalling pathway define hairy and slick cattle.催乳素信号通路的功能互补性突变决定了有毛和无毛牛的差异。
Nat Commun. 2014 Dec 18;5:5861. doi: 10.1038/ncomms6861.
7
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BMC Genomics. 2014 Dec 15;15(1):1105. doi: 10.1186/1471-2164-15-1105.
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J Anim Sci. 2014 Dec;92(12):5382-93. doi: 10.2527/jas.2014-8211.
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