McLean M A, Freas R B
Anal Chem. 1989 Sep 15;61(18):2054-8. doi: 10.1021/ac00193a011.
Modifications to a thermospray vaporizer probe and ion source have been made that enhance ion evaporation resulting in increased sample ion current. These modifications include restricting the thermospray vaporizer exit orifice and the addition of a needle-tip repeller electrode to the thermospray ion source. The interaction and effect of probe-tip size, repeller voltage, and flow rate on sulfonated azo dye detection are reported. An increase in signal response for sulfonated azo dyes was observed. An efficient chromatographic separation procedure for sulfonated azo dyes, which is compatible with thermospray mass spectrometric detection, is also presented. Five disulfonated azo dyes were separated and detected by using selected ion monitoring. Mass spectra of disulfonated dyes show a number of molecular ions and adduct ions that provide unequivocal molecular weight information.
对热喷雾蒸发器探头和离子源进行了改进，以增强离子蒸发，从而提高样品离子电流。这些改进包括限制热喷雾蒸发器出口孔，并在热喷雾离子源中添加针尖排斥电极。报道了探头尖端尺寸、排斥电压和流速对磺化偶氮染料检测的相互作用和影响。观察到磺化偶氮染料的信号响应有所增加。还提出了一种与热喷雾质谱检测兼容的磺化偶氮染料高效色谱分离方法。通过选择离子监测对五种二磺化偶氮染料进行了分离和检测。二磺化染料的质谱显示了许多分子离子和加合离子，提供了明确的分子量信息。
