Prakaschandra Rosaley, Naidoo Datshana P
Department of Biomedical and Clinical Technology, Durban University of Technology, South Africa.
Department of Cardiology, University of KwaZulu-Natal, South Africa.
Diabetes Metab Syndr. 2017 Nov;11 Suppl 1:S81-S85. doi: 10.1016/j.dsx.2016.12.011. Epub 2016 Dec 15.
There is no current evidence available on the prevalence of metabolic syndrome (MetS) in South African Asian Indians, who are at high risk for cardiovascular disease. The aim of our study was to determine the prevalence of the MetS in this group, between males and females, as well as in the different age-groups, using the harmonised criteria and determined the main components driving the development of MetS.
This cross-sectional study recruited randomly selected community participants between the ages of 15 and 65 years, in the community of Phoenix, in KwaZulu-Natal. All subjects had anthropometric variables and blood pressure measured, as well as blood drawn for blood glucose and lipids after overnight fasting. The MetS was determined using the harmonised criteria.
There were 1378 subjects sampled, mean age 45.5±13years and 1001 (72.6%) women. The age standardised prevalence for MetS was 39.9% and significantly higher (p<0.001) in women (49.9% versus 35.0% in men). The MetS was identified in 6.9% of young adults (15-24 years), with a four-fold increase in the 25-34year olds, and 60.1% in the 55-64year old group. Clustering of MetS components was present in all age-groups, but increased with advancing age. The independent contributors to the MetS were increased waist circumference, raised triglycerides and obesity. This study highlights the high prevalence of MetS in this ethnic group and the emergence of MetS in our younger subjects. Urgent population-based awareness campaigns, focussing on correcting unhealthy lifestyle behaviours should begin in childhood.
目前尚无关于南非亚洲印度人代谢综合征（MetS）患病率的证据，而该群体患心血管疾病的风险很高。我们研究的目的是使用统一标准确定该群体中MetS的患病率、男性和女性之间以及不同年龄组中的患病率，并确定推动MetS发展的主要因素。
这项横断面研究在夸祖鲁 - 纳塔尔省凤凰城社区随机招募了15至65岁的社区参与者。所有受试者均测量了人体测量学变量和血压，并在空腹过夜后采集血液检测血糖和血脂。使用统一标准确定MetS。
共采样1378名受试者，平均年龄45.5±13岁，女性1001名（72.6%）。MetS的年龄标准化患病率为39.9%，女性患病率显著更高（p<0.001）（49.9%对男性的35.0%）。在6.9%的年轻人（15 - 24岁）中发现了MetS，25 - 34岁年龄段增加了四倍，55 - 64岁组中为60.1%。MetS各组分的聚集在所有年龄组中均存在，但随年龄增长而增加。MetS的独立影响因素是腰围增加、甘油三酯升高和肥胖。这项研究突出了该种族群体中MetS的高患病率以及年轻受试者中MetS的出现。应在儿童时期就开展基于人群的紧急宣传活动，重点是纠正不健康的生活方式行为。
