IRCCS SDN, Via E. Gianturco 113, 80143 Naples, Italy.
Unit of Cardiology, San Gennaro Hospital, ASL Napoli 1 Centro, Via San Gennaro 25, 80100 Naples, Italy.
Eur Heart J Cardiovasc Imaging. 2017 Nov 1;18(11):1229-1235. doi: 10.1093/ehjci/jew218.
Coronary artery aneurysms (CAAs) are incidentally revealed by coronary angiography and consist in a localized dilation of a coronary artery. Although invasive coronary angiography (ICA) is the gold standard imaging technique, it can lead to the underestimation of CAAs diameter in presence of parietal thrombi. Computed tomography coronary angiography (CTCA) is a very sensitive tool in CAAs detection and provides a clear visualization of coronary lumen highlighting intraluminal thrombi.
We retrospectively reviewed 390 CTCA performed at our institution, 9 patients (6 men, 3 women) resulted affected by CAAs and represented the aneurysmal group (A group). Matched controls were identified among the non-aneurysmal patients with healthy coronaries to CTCA (NAH group). Clinical variables and imaging findings were compared and correlated. CAAs prevalence in our population was 2.31%. 15 CAAs were detected, mainly on the right coronary artery (RCA) (9 aneurysms) followed by the left anterior descending coronary artery (LAD) (three aneurysms) and the left circumflex coronary artery (CX) (three aneurysms). In six patients (66.7%) CTCA displayed an aneurysmal thrombosis and in 5 patients (55.5%) CAAs were associated to coronary artery stenoses. A statistically significant difference was found between the diameters of coronary vessels measured in healthy segments in A and NAH group.
CTCA has led to a non-invasive estimation of CAAs prevalence and characterization of aneurysmal features and coronary anatomy. Overcoming ICA limitations, CTCA has provided a fine analysis of the aneurysms, also in presence of intraluminal thrombi.
冠状动脉瘤是通过冠状动脉造影偶然发现的,表现为冠状动脉的局部扩张。尽管有创性冠状动脉造影(ICA)是金标准成像技术,但在存在壁血栓的情况下,它可能导致冠状动脉瘤直径的低估。计算机断层冠状动脉造影(CTCA)是检测冠状动脉瘤的一种非常敏感的工具,可以清晰地显示冠状动脉管腔,突出腔内血栓。
我们回顾性地分析了在我院进行的 390 例 CTCA,其中 9 例患者(6 名男性,3 名女性)患有冠状动脉瘤,代表了动脉瘤组(A 组)。在无冠状动脉瘤的健康冠状动脉 CTCA 患者中确定了匹配的对照组(NAH 组)。比较并相关分析了临床变量和影像学发现。在我们的人群中,冠状动脉瘤的患病率为 2.31%。共发现 15 个冠状动脉瘤,主要位于右冠状动脉(RCA)(9 个动脉瘤),其次是左前降支冠状动脉(LAD)(3 个动脉瘤)和左回旋支冠状动脉(CX)(3 个动脉瘤)。在 6 例患者(66.7%)中,CTCA 显示动脉瘤血栓形成,5 例(55.5%)患者伴有冠状动脉狭窄。在 A 组和 NAH 组的健康节段中,测量的冠状动脉直径存在统计学显著差异。
CTCA 实现了对冠状动脉瘤患病率的非侵入性评估,以及对动脉瘤特征和冠状动脉解剖结构的准确评估。克服了 ICA 的局限性,CTCA 还可以在存在腔内血栓的情况下对动脉瘤进行精细分析。