Yoshida H, Kajimoto G
Department of Nutrition, Kobe-Gakuin University, Japan.
Ann Nutr Metab. 1989;33(3):153-61. doi: 10.1159/000177532.
Tocopherol, one of the antioxidants in vegetable fats and oils, was added to the autoxidized diet of male rats at the same tocopherol level as soybean oil before autoxidation. Autoxidized soybean oil was used as the test lipid; fresh soybean oil was the control. The diet containing autoxidized oil depressed the body weight gains and increased the tissue ratios to body weight, with the exception of testicle. Parallel with those, increased hemolysis, peroxide value and carbonyl value in the tissue lipids, and a decrease in linoleic or arachidonic acid was observed. The effect of dietary vitamin E on the tissue lipid peroxidation was different among the individual organs. From the results obtained by chemical analyses, the lipid peroxidation caused in the liver, heart and intestine was recognized to be suppressed effectively when the same tocopherol level as fresh soybean oil was added to the diet.
生育酚是植物油中的抗氧化剂之一，在雄性大鼠的自氧化饮食中添加的生育酚水平与大豆油自氧化前的水平相同。使用自氧化大豆油作为受试脂质；新鲜大豆油作为对照。含有自氧化油的饮食会抑制体重增加，并增加组织与体重的比率，但睾丸除外。与此同时，观察到组织脂质中的溶血、过氧化值和羰基值增加，亚油酸或花生四烯酸减少。饮食中维生素E对各器官组织脂质过氧化的影响各不相同。从化学分析结果来看，当在饮食中添加与新鲜大豆油相同水平的生育酚时，肝脏、心脏和肠道中引起的脂质过氧化被认为得到了有效抑制。
