Roh Eun, Kim Min Seon
Department of Biomedical Science, University of Ulsan College of Medicine, Seoul, Korea.
Division of Endocrinology and Metabolism, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Endocrinol Metab (Seoul). 2016 Dec;31(4):519-524. doi: 10.3803/EnM.2016.31.4.519.
In healthy individuals, energy intake is in balance with energy expenditure, which helps to maintain a normal body weight. The brain's inability to control energy homeostasis underlies the pathology of hyperphagia and obesity. The brain detects body energy excess and deficit by sensing the levels of circulating metabolic hormones and nutrients and by receiving metabolic information from the periphery via the autonomic nervous system. A specialized neuronal network coordinates energy intake behavior and the metabolic processes affecting energy expenditure. Here, we briefly review neuronal mechanisms by which our body maintains energy balance.
在健康个体中，能量摄入与能量消耗保持平衡，这有助于维持正常体重。大脑无法控制能量稳态是导致食欲亢进和肥胖的病理基础。大脑通过感知循环代谢激素和营养物质的水平，并通过自主神经系统从外周接收代谢信息，来检测身体能量的过剩和不足。一个专门的神经元网络协调能量摄入行为和影响能量消耗的代谢过程。在此，我们简要回顾一下身体维持能量平衡的神经元机制。
