在局部麻醉溶液中使用去氨加压素和肾上腺素的混合物以获得更有效的血管收缩作用。
The use of mixtures of octapressin and adrenaline in local anaesthetic solutions to obtain more effective vasoconstriction.
作者信息
Gerke D C, Halloran T N, Frewin D B, Frost B R
出版信息
Aust Dent J. 1978 Jun;23(3):240-3. doi: 10.1111/j.1834-7819.1978.tb05173.x.
Abstract
The synergistic effects of felypressin with adrenaline have been studied using the isolated central artery of the rabbit ear as a vascular model. Sub-constrictor doses of felypressin were shown to increase adrenaline's vasoconstrictor effect on this vessel. It is therefore suggested that a mixture of felypressin and adrenaline be used in local anaesthetic solutions in order to provide more effective vasoconstriction.
摘要
以兔耳离体中央动脉作为血管模型，研究了去氧肾上腺素与肾上腺素的协同效应。结果表明，低于收缩剂量的去氧肾上腺素可增强肾上腺素对该血管的血管收缩作用。因此，建议在局部麻醉溶液中使用去氧肾上腺素与肾上腺素的混合物，以实现更有效的血管收缩。
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