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医疗急救团队启动的时机和地点与结局的严重性相关:一项三级医院的观察性研究。

Timing and Location of Medical Emergency Team Activation Is Associated with Seriousness of Outcome: An Observational Study in a Tertiary Care Hospital.

作者信息

Kurita Takeo, Nakada Taka-Aki, Kawaguchi Rui, Shinozaki Koichiro, Abe Ryuzo, Oda Shigeto

机构信息

Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, Chiba, Japan.

The Feinstein Institute for Medical Research, Manhasset, New York, United States of America.

出版信息

PLoS One. 2016 Dec 28;11(12):e0168729. doi: 10.1371/journal.pone.0168729. eCollection 2016.

Abstract

PURPOSE

The medical emergency team (MET) can be activated anytime and anywhere in a hospital. We hypothesized the timing and location of MET activation are associated with seriousness of outcome.

MATERIALS AND METHODS

We tested for an association of clinical outcomes with timing and location using a university hospital cohort in Japan (n = 328). The primary outcome was short-term serious outcome (unplanned ICU admission after MET activation or death at scene).

RESULTS

Patients for whom the MET was activated in the evening or night-time had significantly higher rates of short-term serious outcome than those for whom it was activated during the daytime (vs. evening: adjusted OR = 2. 53, 95% CI = 1.24-5.13, P = 0.010; night-time: adjusted OR = 2.45, 95% CI = 1.09-5.50, P = 0.030). Patients for whom the MET was activated in public space had decreased short-term serious outcome compared to medical spaces (public space: adjusted OR = 0.19, 95% CI = 0.07-0.54, P = 0.0017). Night-time (vs. daytime) and medical space (vs. public space) were significantly associated with higher risks of unexpected cardiac arrest and 28-day mortality.

CONCLUSIONS

Patients for whom the MET was activated in the evening/night-time, or in medical space, had a higher rate of short-term serious outcomes. Taking measures against these risk factors may improve MET performance.

摘要

目的

医疗急救团队(MET)可在医院内随时随地启动。我们推测MET启动的时间和地点与预后的严重性相关。

材料与方法

我们使用日本一家大学医院的队列(n = 328),测试临床结局与启动时间和地点之间的关联。主要结局是短期严重结局(MET启动后非计划入住重症监护病房或在现场死亡)。

结果

在傍晚或夜间启动MET的患者,其短期严重结局的发生率显著高于在白天启动MET的患者(与傍晚相比:校正比值比=2.53,95%置信区间=1.24 - 5.13,P = 0.010;夜间:校正比值比=2.45,95%置信区间=1.09 - 5.50,P = 0.030)。与在医疗空间启动MET的患者相比,在公共空间启动MET的患者短期严重结局有所减少(公共空间:校正比值比=0.19,95%置信区间=0.07 - 0.54,P = 0.0017)。夜间(与白天相比)和医疗空间(与公共空间相比)与意外心脏骤停和28天死亡率的较高风险显著相关。

结论

在傍晚/夜间或医疗空间启动MET的患者,短期严重结局的发生率较高。针对这些风险因素采取措施可能会改善MET的表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/044c/5193425/7295974ddfa7/pone.0168729.g001.jpg

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