Felicio L F, Palermo-Neto J, Nasello A G
Clinical Pharmacology and Toxicology, School of Veterinary Medicine, University of São Paulo, Brazil.
Behav Neural Biol. 1989 Sep;52(2):145-51. doi: 10.1016/s0163-1047(89)90257-4.
Effects of different perinatal bromopride treatments on sexual behavior were examined in adult male and female rats of Wistar origin. Female rats of mothers treated with bromopride (BRO) during lactation (VB group) and during pregnancy and lactation (BB group) showed lower lordosis quotients than those of controls (VV group). Females of mothers treated with BRO only during pregnancy (BV group) showed no differences in lordosis quotient when compared to the VV group. There were no significant differences in male sexual behavior between experimental and control groups. The effect of bromopride on the control of sexual behavior is discussed.
研究了围产期不同时间给予溴必利处理对Wistar成年雌雄大鼠性行为的影响。在哺乳期接受溴必利(BRO)处理的母鼠所生雌性大鼠(VB组)以及在孕期和哺乳期均接受溴必利处理的母鼠所生雌性大鼠(BB组),其脊柱前凸商低于对照组(VV组)。仅在孕期接受溴必利处理的母鼠所生雌性大鼠(BV组),与VV组相比,脊柱前凸商无差异。实验组和对照组之间的雄性性行为无显著差异。文中讨论了溴必利对性行为控制的影响。