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斑贴试验后时间和对试验结果的回忆对生活质量(QoL)的影响。对 1 、 5 和 10 年后手部湿疹患者进行斑贴试验后 QoL 的横断面研究。

Effects of time and recall of patch test results on quality of life (QoL) after testing. Cross-sectional study analyzing QoL in hand eczema patients 1, 5 and 10 years after patch testing.

机构信息

Department of Dermatology, School of Medical Sciences, Örebro University Hospital, 701 85, Örebro.

Faculty of Medicine, Section of Medical Sciences, Örebro University, 701 82, Örebro, Sweden.

出版信息

Contact Dermatitis. 2017 Aug;77(2):88-94. doi: 10.1111/cod.12734. Epub 2016 Dec 28.

Abstract

BACKGROUND

Patch testing can improve health-related quality of life (HRQOL).

OBJECTIVES

To study the impact on HRQOL of elapsed time after patch testing (1-10 years), and how the outcome of testing and patients' recall affects HRQOL.

PATIENTS/MATERIALS/METHODS: The Dermatology Life Quality Index (DLQI) questionnaire was sent to all patients (aged 18-65 years) who were patch tested for suspected contact allergy in 2009, 2005 and 2000 at the Department of Dermatology in Örebro.

RESULTS

The response rate was 51% (n = 256). The DLQI score was significantly lower at 10 years after patch testing (mean DLQI = 5.5) than at 1 year (mean DLQI = 7.7). Work was the most impaired aspect. A binary logistic model showed that only time (10 years after testing) was associated with no effect, a light effect or a moderate effect (DLQI < 10) on HRQOL. No such association was seen for patients with negative or positive test results concerning full recall, partial recall or no recall of diagnosed allergens.

CONCLUSIONS

Although there was an improvement in HRQOL over time, the work aspect remained a major problem. The improvement was not affected by the outcome of testing and patients' recall of test results.

摘要

背景

斑贴试验可以改善健康相关生活质量(HRQOL)。

目的

研究斑贴试验后时间(1-10 年)对 HRQOL 的影响,以及试验结果和患者回忆如何影响 HRQOL。

患者/材料/方法:向在 2009 年、2005 年和 2000 年在厄勒布鲁皮肤科接受可疑接触过敏斑贴试验的所有(18-65 岁)患者发送皮肤病生活质量指数(DLQI)问卷。

结果

应答率为 51%(n=256)。斑贴试验 10 年后的 DLQI 评分明显低于 1 年(平均 DLQI=7.7)。工作是受影响最严重的方面。二元逻辑模型显示,只有时间(试验后 10 年)与 HRQOL 无影响、轻度影响或中度影响(DLQI<10)相关。对于完全回忆、部分回忆或未回忆诊断过敏原的阴性或阳性试验结果的患者,没有观察到这种关联。

结论

尽管随着时间的推移 HRQOL 有所改善,但工作方面仍然是一个主要问题。这种改善不受测试结果和患者对测试结果的回忆的影响。

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