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评估皮炎患者的生活质量(QoL)以及斑贴试验对 QoL 的影响:一项对 519 例皮炎患者的研究。

Assessment of the quality of life (QoL) of patients with dermatitis and the impact of patch testing on QoL: A study of 519 patients diagnosed with dermatitis.

机构信息

Department of Dermatology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Department of Occupational and Environmental Dermatology, Lund University, Skåne University Hospital, Malmö, Sweden.

出版信息

Contact Dermatitis. 2020 Sep;83(3):182-188. doi: 10.1111/cod.13535. Epub 2020 Apr 20.

Abstract

BACKGROUND

Dermatitis can impair the quality of life (QoL) of patients. Knowledge of the QoL-associated factors and the impact of patch testing on QoL is limited.

OBJECTIVES

To identify demographic and clinical factors affecting QoL, and to measure the impact of patch testing on QoL of dermatitis patients.

METHODS

The data and Dermatology Life Quality Index (DLQI) questionnaires of 519 dermatitis patients were analyzed. Of these, 107 underwent patch testing and completed the questionnaires two times (once before testing and again 60 days afterward).

RESULTS

The overall mean (±standard deviation) DLQI was 9.5 (±6.4). Patients aged 20 to 59 years and those who had more frequent disease exacerbations demonstrated significantly higher DLQIs. For each DLQI question, being female and aged 20 to 59 years were associated with impairments of various aspects of life, whereas the anatomical site of dermatitis impacted each question differently. The DLQI scores of the patients undergoing patch testing decreased significantly, irrespective of whether the test results were positive or negative.

CONCLUSIONS

Being of a working age and having more frequent disease exacerbations had negative QoL impacts. In addition, patch testing improved almost every aspect of the DLQI.

摘要

背景

皮炎会影响患者的生活质量(QoL)。人们对与 QoL 相关的因素以及斑贴试验对 QoL 的影响了解有限。

目的

确定影响 QoL 的人口统计学和临床因素,并测量斑贴试验对皮炎患者 QoL 的影响。

方法

分析了 519 名皮炎患者的数据和皮肤病生活质量指数(DLQI)问卷。其中,有 107 名患者进行了斑贴试验,并在两次完成了问卷(一次在测试前,另一次在 60 天后)。

结果

总体平均(±标准偏差)DLQI 为 9.5(±6.4)。20 至 59 岁的患者和疾病发作更频繁的患者的 DLQI 明显更高。对于每个 DLQI 问题,女性和 20 至 59 岁的年龄与生活各方面的损害有关,而皮炎的解剖部位对每个问题的影响不同。无论试验结果是阳性还是阴性,进行斑贴试验的患者的 DLQI 评分均显著下降。

结论

处于工作年龄和疾病发作更频繁对 QoL 有负面影响。此外,斑贴试验改善了 DLQI 的几乎所有方面。

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