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巴基斯坦口腔鳞状细胞癌延迟诊断的频率。

Frequency of Delayed Diagnosis of Oral Squamous Cell Carcinoma in Pakistan.

作者信息

Naseer Rabia, Naz Iram, Mahmood Muhammad Khurram

机构信息

Oral and Maxillofacial Surgery, University College of Dentistry, University of Lahore, Lahore, Pakistan. Email:

出版信息

Asian Pac J Cancer Prev. 2016 Nov 1;17(11):5037-5040. doi: 10.22034/APJCP.2016.17.11.5037.

Abstract

Objectives: To determine the frequency of delayed diagnosis of oral squamous cell carcinoma in our setup; highlighting factors responsible for any delay and their possible relevance to demographic and diagnostic features. Methods: This cross sectional study of six months duration was conducted in the Oral and Maxillofacial Surgery Department of the Armed Forces Institute of Dentistry, Rawalpindi, Pakistan. A total of 246 patients, both male and female, having a biopsy proven definitive diagnosis of OSCC were included using a consecutive sampling technique. Delay in diagnosis was assessed from the stated period of time from when the patient first noticed symptoms of disease until a definitive diagnosis was made. We concluded delayed diagnosis if this was more than 40 days. Results: The ages of patients ranged from 27 to 60 years with a mean of 46.7 ± 10.2 years and a marked male predominance (3.7:1). Delayed diagnosis was observed in 91.5% of cases. However, statistically no significant differences were found with age, gender, marital, education status, household income and time of biopsy. Conclusion: Our primary finding of delayed diagnosis with no prior contact with any health care professional clearly reflects a need of taking urgent measures to avoid serious impacts on morbidity and mortality associated with OSCC.

摘要

目的

确定在我们的机构中口腔鳞状细胞癌延迟诊断的频率;突出导致延迟的因素及其与人口统计学和诊断特征的可能关联。方法:这项为期六个月的横断面研究在巴基斯坦拉瓦尔品第武装部队牙科学院口腔颌面外科进行。采用连续抽样技术,纳入了总共246例经活检确诊为口腔鳞状细胞癌的患者,男女均有。从患者首次注意到疾病症状到确诊的规定时间段来评估诊断延迟情况。如果超过40天,我们判定为延迟诊断。结果:患者年龄在27至60岁之间,平均年龄为46.7±10.2岁,男性占明显优势(3.7:1)。91.5%的病例观察到延迟诊断。然而,在年龄、性别、婚姻状况、教育程度、家庭收入和活检时间方面,未发现统计学上的显著差异。结论:我们关于延迟诊断且患者此前未接触任何医疗保健专业人员的主要发现清楚地表明,需要采取紧急措施,以避免对与口腔鳞状细胞癌相关的发病率和死亡率产生严重影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/43d8/5454716/3995885fc303/APJCP-17-5037-g001.jpg

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