Koyama Shouhei, Ishizawa Hiroaki, Fujimoto Keisaku, Chino Shun, Kobayashi Yuka
Institute for Fiber Engineering, Shinshu University, 3-15-1 Tokida, Ueda City, Nagano 386-8567, Japan.
Department of Clinical Laboratory Sciences, School of Health Sciences, Shinshu University, 3-1-1 Asahi, Matsumoto City, Nagano 390-8621, Japan.
Sensors (Basel). 2016 Dec 28;17(1):48. doi: 10.3390/s17010048.
In this paper, we propose a blood pressure calculation and associated measurement method that by using a fiber Bragg grating (FBG) sensor. There are several points at which the pulse can be measured on the surface of the human body, and when a FBG sensor located at any of these points, the pulse wave signal can be measured. The measured waveform is similar to the acceleration pulse wave. The pulse wave signal changes depending on several factors, including whether or not the individual is healthy and/or elderly. The measured pulse wave signal can be used to calculate the blood pressure using a calibration curve, which is constructed by a partial least squares (PLS) regression analysis using a reference blood pressure and the pulse wave signal. In this paper, we focus on the influence of individual differences from calculated blood pressure based on each calibration curve. In our study, the calculated blood pressure from both the individual and overall calibration curves were compared, and our results show that the calculated blood pressure based on the overall calibration curve had a lower measurement accuracy than that based on an individual calibration curve. We also found that the influence of the individual differences on the calculated blood pressure when using the FBG sensor method were very low. Therefore, the FBG sensor method that we developed for measuring the blood pressure was found to be suitable for use by many people.
在本文中,我们提出了一种利用光纤布拉格光栅(FBG)传感器的血压计算及相关测量方法。在人体表面有几个可以测量脉搏的点,当FBG传感器位于这些点中的任何一个时,就可以测量脉搏波信号。所测量的波形类似于加速度脉搏波。脉搏波信号会因多种因素而变化,包括个体是否健康和/或是否年老。所测量的脉搏波信号可用于通过校准曲线来计算血压,该校准曲线是通过使用参考血压和脉搏波信号的偏最小二乘(PLS)回归分析构建的。在本文中,我们重点关注基于每条校准曲线计算出的血压中个体差异的影响。在我们的研究中,对基于个体校准曲线和总体校准曲线计算出的血压进行了比较,结果表明,基于总体校准曲线计算出的血压测量精度低于基于个体校准曲线计算出的血压。我们还发现,使用FBG传感器方法时个体差异对计算出的血压的影响非常小。因此,我们开发的用于测量血压的FBG传感器方法被发现适用于许多人。