Yang Doyle, Keys Brandon, J Conti David, Foulke Llewellyn, Stellrecht Kathleen, Cook Linda, Lopez-Soler Reynold I
Department of Surgery, Albany Medical College, Albany, NY, USA.
Division of Surgery, Section of Transplantation, Albany Medical Center, Albany, NY, USA.
Transpl Infect Dis. 2017 Apr;19(2). doi: 10.1111/tid.12654. Epub 2017 Feb 22.
JC polyomavirus-associated nephropathy (JC-PVAN) is a rare but challenging cause of renal dysfunction. We report JC-PVAN in a renal allograft recipient and highlight the obstacles in definitive diagnosis of this disease entity. A deceased-donor renal transplant recipient was diagnosed with JC polyomavirus nephritis 4 years after transplantation. Immunosuppressive agents were subsequently reduced, resulting in an initial stabilization of renal function. We present this interesting case and discuss the challenges with diagnosing and treating this rare entity.
JC多瘤病毒相关肾病（JC-PVAN）是一种罕见但具有挑战性的肾功能障碍病因。我们报告了1例肾移植受者的JC-PVAN，并强调了确诊该疾病实体的障碍。1例尸体供肾移植受者在移植后4年被诊断为JC多瘤病毒肾炎。随后减少了免疫抑制剂的用量，肾功能初步稳定。我们展示了这个有趣的病例，并讨论了诊断和治疗这种罕见疾病的挑战。
