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NCCN 指南解读:遗传/家族性高风险评估:乳腺和卵巢,2017 年第 2 版。

NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2017.

机构信息

Fox Chase Cancer Center

The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute

出版信息

J Natl Compr Canc Netw. 2017 Jan;15(1):9-20. doi: 10.6004/jnccn.2017.0003.

Abstract

The NCCN Clinical Practice Guidelines in Oncology for Genetic/Familial High-Risk Assessment: Breast and Ovarian provide recommendations for genetic testing and counseling for hereditary cancer syndromes and risk management recommendations for patients who are diagnosed with a syndrome. Guidelines focus on syndromes associated with an increased risk of breast and/or ovarian cancer. The NCCN Genetic/Familial High-Risk Assessment: Breast and Ovarian panel meets at least annually to review comments from reviewers within their institutions, examine relevant new data from publications and abstracts, and reevaluate and update their recommendations. The NCCN Guidelines Insights summarize the panel's discussion and most recent recommendations regarding risk management for carriers of moderately penetrant genetic mutations associated with breast and/or ovarian cancer.

摘要

NCCN 肿瘤学遗传/家族性高风险评估临床实践指南:乳腺和卵巢为遗传性癌症综合征的基因检测和咨询提供建议,并为诊断出综合征的患者提供风险管理建议。指南侧重于与乳腺癌和/或卵巢癌风险增加相关的综合征。NCCN 遗传/家族性高风险评估:乳腺和卵巢专家组至少每年开会一次,审议其机构内评审人的意见,检查出版物和摘要中相关的新数据,并重新评估和更新其建议。NCCN 指南洞察总结了专家组关于与乳腺和/或卵巢癌相关的中度外显率遗传突变携带者的风险管理的讨论和最新建议。

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