1 Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota; and.
2 Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Am J Respir Crit Care Med. 2017 Mar 15;195(6):725-736. doi: 10.1164/rccm.201609-1767CI.
Despite significant advances in our understanding and management of patients with acute respiratory distress syndrome (ARDS), the morbidity and mortality from ARDS remains high. Given the limited number of effective treatments for established ARDS, the strategic focus of ARDS research has shifted toward identifying patients with or at high risk of ARDS early in the course of the underlying illness, when strategies to reduce the development and progression of ARDS and associated organ failures can be systematically evaluated. In this review, we summarize the rationale, current evidence, and future directions in ARDS prevention.
尽管我们在理解和治疗急性呼吸窘迫综合征（ARDS）患者方面取得了重大进展，但 ARDS 的发病率和死亡率仍然很高。鉴于目前对 ARDS 有效的治疗方法有限，ARDS 研究的战略重点已转向在潜在疾病过程中尽早识别出患有 ARDS 或有发生 ARDS 高风险的患者，以便能够系统地评估预防 ARDS 和相关器官衰竭的策略。在这篇综述中，我们总结了 ARDS 预防的原理、当前证据和未来方向。
