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是否应提供体外膜肺氧合?一项国际调查。

Should Extracorporeal Membrane Oxygenation Be Offered? An International Survey.

作者信息

Kuo Kevin W, Barbaro Ryan P, Gadepalli Samir K, Davis Matthew M, Bartlett Robert H, Odetola Folafoluwa O

机构信息

Division of Pediatric Critical Care, Department of Pediatrics, University of Michigan, Ann Arbor, MI.

Division of Pediatric Critical Care, Department of Pediatrics, University of Michigan, Ann Arbor, MI.

出版信息

J Pediatr. 2017 Mar;182:107-113. doi: 10.1016/j.jpeds.2016.12.025. Epub 2016 Dec 30.

Abstract

OBJECTIVES

To assess the current attitudes of extracorporeal membrane oxygenation (ECMO) program directors regarding eligibility for ECMO among children with cardiopulmonary failure.

STUDY DESIGN

Electronic cross-sectional survey of ECMO program directors at ECMO centers worldwide within the Extracorporeal Life Support Organization directory (October 2015-December 2015).

RESULTS

Of 733 eligible respondents, 226 (31%) completed the survey, 65% of whom routinely cared for pediatric patients. There was wide variability in whether respondents would offer ECMO to any of the 5 scenario patients, ranging from 31% who would offer ECMO to a child with trisomy 18 to 76% who would offer ECMO to a child with prolonged cardiac arrest and indeterminate neurologic status. Even physicians practicing the same specialty sometimes held widely divergent opinions, with 50% of pediatric intensivists stating they would offer ECMO to a child with severe developmental delay and 50% stating they would not. Factors such as quality of life and neurologic status influenced decision making and were used to support decisions for and against offering ECMO.

CONCLUSIONS

ECMO program directors vary widely in whether they would offer ECMO to various children with cardiopulmonary failure. This heterogeneity in physician decision making underscores the need for more evidence that could eventually inform interinstitutional guidelines regarding patient selection for ECMO.

摘要

目的

评估体外膜肺氧合(ECMO)项目主任对心肺衰竭儿童接受ECMO治疗资格的当前态度。

研究设计

对体外生命支持组织名录(2015年10月 - 2015年12月)中全球ECMO中心的ECMO项目主任进行电子横断面调查。

结果

在733名符合条件的受访者中,226名(31%)完成了调查,其中65%的人常规护理儿科患者。对于5种情景患者中的任何一位是否提供ECMO,受访者的态度差异很大,从31%会为18三体综合征患儿提供ECMO到76%会为心脏骤停时间延长且神经状态不确定的患儿提供ECMO。即使是从事同一专业的医生有时也持有广泛不同的意见,50%的儿科重症监护医生表示他们会为严重发育迟缓的患儿提供ECMO,50%表示不会。生活质量和神经状态等因素影响决策,并被用于支持提供或不提供ECMO的决策。

结论

ECMO项目主任对于是否为各类心肺衰竭儿童提供ECMO的态度差异很大。医生决策的这种异质性强调了需要更多证据,最终为关于ECMO患者选择的机构间指南提供依据。

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